D-(+)-Mannose

Name: <SC>D</SC>-(+)-Mannose
Brand: SIGMA

BioUltra, ≥99.5% (sum of enantiomers, HPLC)

Synonym(s):

D-Mannopyranose

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₂O₆

CAS Number:

3458-28-4

Molecular Weight:

180.16

UNSPSC Code:

12352201

NACRES:

NA.25

PubChem Substance ID:

57651949

EC Number:

222-392-4

Beilstein/REAXYS Number:

1564373

MDL number:

MFCD00064122

Key Documents

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Product Name

D-(+)-Mannose, BioUltra, ≥99.5% (sum of enantiomers, HPLC)

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1

InChI key

WQZGKKKJIJFFOK-QTVWNMPRSA-N

SMILES string

OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O

product line

BioUltra

assay

≥99.5% (sum of enantiomers, HPLC)

form

solid

optical activity

[α]20/D +13.8±0.5°, 24 hr, c = 10% in H₂O

impurities

insoluble matter, passes filter test

ign. residue

≤0.1% (as SO₄)

loss

≤0.1% loss on drying, 20 °C (HV)

color

white

mp

133-140 °C (lit.)

solubility

H₂O: 1 M, clear, colorless

anion traces

chloride (Cl^-): ≤50 mg/kg
sulfate (SO₄^2-): ≤200 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.5 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤200 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤20 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H₂O

UV absorption

λ: 260 nm A_max: 0.1
λ: 280 nm A_max: 0.1

storage temp.

room temp

Quality Level

200

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Chemistry & Biochemicals

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Show Differences

1 of 4

This Item	63582	M8574	M2069
Sigma-Aldrich 63579 D-(+)-Mannose	Millipore 63582 D-(+)-Mannose	Sigma-Aldrich M8574 D-(+)-Mannose	Sigma-Aldrich M2069 D-(+)-Mannose
assay ≥99.5% (sum of enantiomers, HPLC)	assay ≥99.0% (sum of enantiomers, HPLC)	assay ≥99% (GC)	assay ≥99% (GC)
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
solubility H₂O: 1 M, clear, colorless	solubility H₂O: 0.1 g/mL, clear, colorless	solubility water: soluble 10 g/L at 20 °C	solubility water: 50 mg/mL, clear, colorless to faintly yellow
form solid	form powder	form powder	form powder
storage temp. room temp	storage temp. -	storage temp. room temp	storage temp. room temp
product line BioUltra	product line -	product line -	product line -

Application

D-(+)-Mannose, a C-2 epimer of D-glucose, is used in the formation of glycan structure and glycosylation.

Biochem/physiol Actions

Mannose, a six-carbon carbohydrate, is the C-2 epimer of glucose and a critical sugar for protein glycosylation. Mannose can also be utilized by the brain as an alternative energy source.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

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Microneedle-based intradermal delivery of stabilized dengue virus.

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Bioengineering & translational medicine, 4(2), e10127-e10127 (2019-06-30)

Current live-attenuated dengue vaccines require strict cold chain storage. Methods to preserve dengue virus (DENV) viability, which enable vaccines to be transported and administered at ambient temperatures, will be decisive towards the implementation of affordable global vaccination schemes with broad

Single-run HPLC Quantification of Plant Cell Wall Monosaccharides.

Alexandra Menna et al.

Bio-protocol, 10(5), e3546-e3546 (2021-03-05)

The plant cell wall is a complex network of polysaccharides and proteins that provides strength and structural integrity to plant cells, as well as playing a vital role in growth, development, and defense response. Cell wall polysaccharides can be broadly

Isolation and characterization of the mannose receptor from human liver potentially involved in the plasma clearance of tissue-type plasminogen activator.

M Otter et al.

Hepatology (Baltimore, Md.), 16(1), 54-59 (1992-07-01)

Various studies have shown that mannose receptors rapidly eliminate glycoproteins and microorganisms bearing high mannose-type carbohydrate chains from the blood circulation. The purpose of this study was to characterize the mannose receptor in the liver, which in vivo is involved

Intravenous administration of phosphorylated acid alpha-glucosidase leads to uptake of enzyme in heart and skeletal muscle of mice.

A T Van der Ploeg et al.

The Journal of clinical investigation, 87(2), 513-518 (1991-02-01)

The lysosomal storage disorder glycogenosis type II is caused by acid alpha-glucosidase deficiency. In this study we have investigated the possible applicability of mannose 6-phosphate receptor-mediated enzyme replacement therapy to correct the enzyme deficiency in the most affected tissues. Bovine

A mannose-specific adherence mechanism in Lactobacillus plantarum conferring binding to the human colonic cell line HT-29.

I Adlerberth et al.

Applied and environmental microbiology, 62(7), 2244-2251 (1996-07-01)

Two Lactobacillus plantarum strains of human intestinal origin, strains 299 (= DSM 6595) and 299v (= DSM 9843), have proved to be efficient colonizers of the human intestine under experimental conditions. These strains and 17 other L. plantarum strains were

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