If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
95144
Retinol
BioXtra, ≥97.5% (HPLC), ~3100 U/mg
Synonym(s):
Axerophthol, Vitamin A, Vitamin A alcohol, Vitamin A1, all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
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Product Name
Retinol, BioXtra, ≥97.5% (HPLC), ~3100 U/mg
InChI key
FPIPGXGPPPQFEQ-OVSJKPMPSA-N
InChI
1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
SMILES string
CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1
biological source
synthetic
product line
BioXtra
assay
≥97.5% (HPLC)
form
(Powder or Powder with Lumps)
specific activity
~3100 U/mg
shelf life
limited shelf life
color
faint yellow to very dark yellow
mp
56-61 °C
61-63 °C (lit.)
shipped in
dry ice
storage temp.
−20°C
Quality Level
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This Item | 17772 | R7632 | R2625 |
|---|---|---|---|
| assay ≥97.5% (HPLC) | assay ≥95.0% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) |
| biological source synthetic | biological source synthetic | biological source synthetic | biological source synthetic (organic) |
| form (Powder or Powder with Lumps) | form (Powder or Crystal with Lumps) | form (Powder or Powder with Lumps) | form powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 200 |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in - |
Application
- as a standard in peak identification and quantification in reverse phase HPLC[1]
- as a standard to estimate the concentration of vitamin A[2]
- to study the inhibitory effect of retinol on murine norovirus (MNV) replication in murine RAW 264.7 cells[3]
- as a component in the reaction mixture for the lecithin:retinol acyltransferase (LRAT) assay[4]
Biochem/physiol Actions
Retinol is biological active in a wide range of processes.
General description
Other Notes
Packaging
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 4 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Protocols
Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.
Related Content
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How can I determine the shelf life / expiration / retest date of this product?
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Bonjour, je souhaiterais acheter du Retinol (CAS : 68-26-8) afin de réaliser une courbe de calibration pour une méthode d'analyse LC-MS/MS. Il me faudrait donc le plus pur possible. Je souhaiterais savoir ce que signifie 3000 U/mg ?
1 answer-
One unit (the USP unit is the same as the International Unit) of vitamin A is equal to 0.3 micrograms of the pure all-trans isomer of retinol, which is equivalent to 0.344 micrograms of all-trans retinyl acetate. This product is ≥97.5% pure by HPLC. More information and references can be found in the data sheet: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/740/736/95144dat.pdf
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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