B6125

N-Benzoyl-L-tyrosine ethyl ester

Name: <I>N</I>-Benzoyl-<SC>L</SC>-tyrosine ethyl ester
Brand: SIGMA

Synonym(s):

BTEE

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About This Item

Linear Formula:

4-(HO)C₆H₄CH₂CH(NHCOC₆H₅)CO₂C₂H₅

CAS Number:

3483-82-7

Molecular Weight:

313.35

NACRES:

NA.25

PubChem Substance ID:

24891896

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

222-469-2

MDL number:

MFCD00002388

Beilstein/REAXYS Number:

2223819

Key Documents

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InChI key

SRLROPAFMUDDRC-INIZCTEOSA-N

InChI

1S/C18H19NO4/c1-2-23-18(22)16(12-13-8-10-15(20)11-9-13)19-17(21)14-6-4-3-5-7-14/h3-11,16,20H,2,12H2,1H3,(H,19,21)/t16-/m0/s1

SMILES string

CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c2ccccc2

form

powder

mp

118-121 °C (lit.)

storage temp.

−20°C

Quality Level

200

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Show Differences

1 of 4

This Item	A6751	B4500	T90808
Sigma-Aldrich B6125 N-Benzoyl-L-tyrosine ethyl ester	Sigma-Aldrich A6751 N-Acetyl-L-tyrosine ethyl ester monohydrate	Sigma-Aldrich B4500 N_α-Benzoyl-L-arginine ethyl ester hydrochloride	Sigma-Aldrich T90808 L-Tyrosine methyl ester
form powder	form powder	form powder	form powder with small lumps
storage temp. −20°C	storage temp. −20°C	storage temp. 2-8°C	storage temp. 2-8°C
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level -
mp 118-121 °C (lit.)	mp -	mp -	mp 134-136 °C (lit.)

Application

N-Benzoyl-L-tyrosine ethyl ester has been used for measuring chymotrypsin activity.[1][2]

General description

N-Benzoyl-L-tyrosine ethyl ester (BTEE) is a substrate which is completely resistant to trypsin and is required for the assay of chymotrypsin.[3]

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Guilbault GG

Enzymatic Methods of Analysis: International Series of Monographs in Analytical Chemistry (201)

Macrophage TNF mRNA expression is modulated by protease inhibitors.

C J Lo et al.

The Journal of surgical research, 69(2), 408-412 (1997-05-01)

Nuclear factor kappa B (NF kappa B) is an important transcriptional activator protein and is a crucial component of the host's response to infection. The activation of NF kappa B is correlated with the phosphorylation of inhibitory kappa B (I

Essential role of NF-kappa B activation in silica-induced inflammatory mediator production in macrophages.

F Chen et al.

Biochemical and biophysical research communications, 214(3), 985-992 (1995-09-25)

In this report, we demonstrate that NF-kappa B, a ubiquitous transcription factor, plays an essential role in silica-induced inflammatory mediator production in the mouse macrophage cell line RAW 264.7. Compared to the effect of lipopolysaccharide (LPS), silica mediated a stronger

Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages.

F Chen et al.

Biochemical and biophysical research communications, 214(3), 839-846 (1995-09-25)

In this report the differential regulation of NF-kappa B and nitric oxide (NO) was investigated in the mouse macrophage cell line RAW 264.7 following exposure to a mineral dust (silica) and/or an endotoxin (Lipopolysaccharide, LPS). The results indicated that silica

Chronic ultraviolet B radiation-induced biochemical changes in the skin of hairless mice.

R Chatterjee et al.

Photochemistry and photobiology, 51(1), 91-97 (1990-01-01)

Skh:HR-1 hairless mice were irradiated chronically with sub-erythemal doses of UVB radiation, and a number of biochemical parameters in the skin were determined after 6, 12, 18, and 24 wk of exposure. The parameters measured were water, collagen, elastin, and

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Articles

Chymotrypsin

Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.

Protocols

Procedure for Enzymatic Assay of α-Chymotrypsin (EC 3.4.21.1)

Follow our procedure for the determination of a chymotrypsin activity. This enzymatic assay of alpha chymotrypsin guides you through the entire process and necessary calculations.

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