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Merck

C1629

Choline bitartrate

Acyl group acceptor, powder

Synonym(s):

2-(Hydroxyethyl)trimethylammonium bitartrate

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About This Item

Empirical Formula (Hill Notation):
C9H19NO7
CAS Number:
Molecular Weight:
253.25
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
EC Number:
201-763-4

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Product Name

Choline bitartrate,

InChI

1S/C5H14NO.C4H6O6/c1-6(2,3)4-5-7;5-1(3(7)8)2(6)4(9)10/h7H,4-5H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/q+1;/p-1/t;1-,2-/m.1/s1

InChI key

QWJSAWXRUVVRLH-LREBCSMRSA-M

SMILES string

[O-]C([C@H](O)[C@@H](O)C(O)=O)=O.C[N+](C)(C)CCO

form

powder

Quality Level

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This Item
1133536PHR1460C7519
form

powder

form

-

form

-

form

liquid

Quality Level

200

Quality Level

-

Quality Level

300

Quality Level

200

Application

Choline bitartrate has been used as one of the components in experimental diets to study the effects on reproductive processes[1] and on bone genes during gestation and lactation.[2]

Biochem/physiol Actions

Acyl group acceptor
Choline bitartrate is known to serve as a dietary supplement. Choline acts as a precursor for acetylcholine synthesis.[3]

General description

Choline acetyltransferase substrate

Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Siamak Sheikhi et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 84(2), 109-121 (2024-02-05)
The mother's thyroid hormone status during gestation and the first few months after delivery can play a crucial role in maturation during the brain development of the child. Transient abnormalities in thyroid function at birth indicate developmental and cognitive disorders
Effects of Diets Enriched in Omega-9 or Omega-6 Fatty Acids on Reproductive Process
Mousavi SN, et al.
Journal of family & reproductive health, 10(2), 85-85 (2016)
Jacob H Murray et al.
Journal of medicinal chemistry, 66(6), 3876-3895 (2023-03-08)
Small-molecule mitochondrial uncouplers are gaining recognition as potential therapeutics for metabolic diseases such as obesity, diabetes, and nonalcoholic steatohepatitis (NASH). Specifically, heterocycles derived from BAM15, a potent and mitochondria-selective uncoupler, have yielded promising preclinical candidates that are efficacious in animal
O T Pantako et al.
Reproduction, nutrition, development, 41(3), 227-238 (2001-10-11)
The effects of two dietary proteins on alpha-amino acids, calcium and phosphorus concentrations in plasma, stomach and intestine were investigated in rats trained to consume, in a single two-hour daily meal, diets containing a-lactalbumin (alpha-la) or whey protein concentrate (WPC)
Yumna Zia et al.
The Journal of nutrition, 148(10), 1513-1520 (2018-10-04)
Phosphatidylethanolamine N-methyltransferase (PEMT) converts phosphatidylethanolamine to phosphatidylcholine. Pemt-/-/low density lipoprotein receptor (Ldlr)-/- mice have significantly reduced plasma lipids and are protected against atherosclerosis. Recent studies have shown that choline can be metabolized by the gut flora into trimethylamine-N-oxide (TMAO), which

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