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Merck

1375502

USP

Mebendazole

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

5-Benzoyl-2-benzimidazolecarbamic acid methyl ester, Mebendazol, Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate

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About This Item

Empirical Formula (Hill Notation):
C16H13N3O3
CAS Number:
31431-39-7
Molecular Weight:
295.29
Beilstein:
759809
MDL number:
MFCD00057872
UNSPSC Code:
41116107
PubChem Substance ID:
329750328
NACRES:
NA.24

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grade

pharmaceutical primary standard

API family

mebendazole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3

InChI

1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)

InChI key

OPXLLQIJSORQAM-UHFFFAOYSA-N

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1 of 4

This Item
M0215000PHR2448M2523
Mebendazole United States Pharmacopeia (USP) Reference Standard

USP

1375502

Mebendazole

Mebendazole European Pharmacopoeia (EP) Reference Standard

M0215000

Mebendazole

Mebendazole Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR2448

Mebendazole

Mebendazole analytical standard, ≥98% (HPLC)

Supelco

M2523

Mebendazole

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

analytical standard

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical small molecule

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

format

neat

format

-

format

neat

API family

mebendazole

API family

mebendazole

API family

mebendazole

API family

-

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Mebendazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Mebendazole Tablets
  • Mebendazole Oral Suspension
  • Fenbendazole
  • Pimozide Tablets
  • Pimozide

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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T Inaoka et al.
[Hokkaido igaku zasshi] The Hokkaido journal of medical science, 62(1), 54-67 (1987-01-01)
The effects of the mebendazole, albendazole and ivermectin on secondary multilocular echinococcosis in Chinese hamsters infected with intraperitoneal inoculation of protoscolices and in rats infected with transportal inoculation of protoscolices were investigated. A reduction in weight of the hydatids greater
R Cañete et al.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 103(5), 437-442 (2009-02-07)
Mebendazole, a benzimidazole carbamate compound, is currently in use for human medical practice against soil-transmitted helminthiasis (STH) and enterobiasis. However, it has been demonstrated that its spectrum of activity is broad and goes beyond those infections. Several studies provide evidence
A Bennett et al.
Parasitology today (Personal ed.), 16(2), 71-74 (2000-02-01)
The widespread use of mebendazole and albendazole for treating intestinal nematode infections in human populations is raising concerns that careful monitoring pro- cedures should be in place to identify any emergence of drug resistance. In this article, Andy Bennett and
Mebendazole and related anthelmintics.
H Van den Bossche et al.
Advances in pharmacology and chemotherapy, 19, 67-128 (1982-01-01)
Olga Staudacher et al.
Tropical medicine & international health : TM & IH, 19(7), 812-824 (2014-04-23)
Preventive chemotherapy of schoolchildren against soil-transmitted helminths (STHs) is widely implemented in Rwanda. However, data on its actual efficacy are lacking. We assessed prevalence, associated factors and manifestation of STH infection among schoolchildren in southern highland Rwanda as well as
View All Related Papers

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