SIRT1
sirtuin 1
Sinónimos:
SIR2L1
Especie:
Human SIRT1 (23411), Mouse Sirt1 (93759), Rat Sirt1 (309757), cow SIRT1 (613629), naked mole-rat Sirt1 (101720282), dog SIRT1 (489012), domestic cat SIRT1 (101087610), chicken SIRT1 (423646), Zebrafish sirt1 (797132), domestic guinea pig Sirt1 (100717014) ...Más
ID UniProtKB:
ID del gen:
- Human(23411) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
- Mouse(93759) sirtuin 1
- Rat(309757) sirtuin 1
- cow(613629) sirtuin 1
- naked mole-rat(101720282) sirtuin 1
- dog(489012) sirtuin 1
- domestic cat(101087610) sirtuin 1
- chicken(423646) sirtuin 1
- Zebrafish(797132) sirtuin (silent mating type information regulation 2 homolog) 1
- domestic guinea pig(100717014) sirtuin 1
- sheep(101102956) sirtuin 1
- Domestic Rabbit(100349271) sirtuin 1
- Horse(100072571) sirtuin 1
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ELISA
Número de producto
Descripción
Especie
Small Molecule - Activator
Número de producto
Descripción
Especie
Activity Assay
Número de producto
Descripción
Especie
Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti Sirtuin 1 Antibody, clone 23GB1610, Rabbit Monoclonal, clone 23GB1610, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-phospho-SIRT1 (Ser47) Antibody, clone 23GB1540, Rabbit Monoclonal, clone 23GB1540, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anticuerpo anti-SIRT1, clon 10E4, clone 10-E-4, from mouse,
Reactividad de especies
human, mouse
Aplicación
ChIP
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-SIRT1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Sirt1 antibody, Mouse monoclonal, clone SIR11, purified from hybridoma cell culture,
Reactividad de especies
mouse
Aplicación
ELISA
microarray
western blot
microarray
western blot
Small Molecule - Inhibitor
Proteins
Número de producto
Descripción
Especie
Sirt1 human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
SIRT1, active, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human