Polypyrimidine tract-binding protein 2 (PTBP2) is also known as Neural polypyrimidine tract-binding protein, Neurally-enriched homolog of PTB and PTB-like protein. PTBP2 is a RNA-binding protein which targets intronic polypyrimidines and negatively regulates pre-mRNA, exonic splicing. PTBP2 also has a role in translational regulation. PTBP2 is mainly expressed in brain, but is also found in heart and skeletal muscle. Isoforms 1 and 2 are specifically expressed in neuronal tissues.
This antibody recognizes the N-terminus of PTBP2.
KLH-conjugated linear peptide corresponding to the N-terminus of human PTBP2.
Research Sub Category
Anti-PTBP2 Antibody is a highly specific rabbit polyclonal antibody, that targets Polypyrimidine tract-binding protein 2 & has been tested in western blotting & IP.
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected PTBP2 in 10 µg of rat brain cortex tissue lysate.
Immunoprecipitation Analysis: 10ug from a representative lot immunoprecipitated PTBP2 in 500 µg of P19 cell lysate.
Epigenetics & Nuclear Function
Evaluated by Western Blotting in human cortex tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected PTBP2 in 10 µg of human cortex tissue lysate.
Descripción de destino
~57 kDa observed. Uncharacterized band(s) may appear in some lysates.
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Almacenamiento y estabilidad
Stable for 1 year at 2-8°C from date of receipt.
Nota de análisis
Human cortex tissue lysate
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.