Merck
All Photos(3)

A3221

Sigma-Aldrich

Iodoacetamide

Single use vial of 56 mg

Linear Formula:
ICH2CONH2
CAS Number:
Molecular Weight:
184.96
Beilstein:
1739080
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.56

Nivel de calidad

200

ensayo

≥99% (HPLC)

formulario

powder

envase

vial of 56 mg (Single use)

mp

92-95 °C (lit.)

solubilidad

H2O: soluble 50 mg/mL, clear, colorless to faintly yellow

temp. de almacenamiento

2-8°C

SMILES string

NC(=O)CI

InChI

1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)

InChI key

PGLTVOMIXTUURA-UHFFFAOYSA-N

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Aplicación

Iodoacetamide may be used as an alkylating reagent for cysteine residues in peptide sequencing and peptide/protein analytical analysis. It may be used in 2-D protein electrophoresis to reduce streaking and improve resolution by eliminating artifacts that could result from disulfide formation during electrophoresis. By virtue of its reaction with cysteine, iodoacetamide is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibition of ribonuclease. Iodoacetamide may be used in disulfide stress research.

Envase

10 vials in glass insert
Packaged in sealed ampules

Acciones bioquímicas o fisiológicas

Iodoacetamide acts as an alkylating reagent for cysteine residues in peptide sequencing. It is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibiting ribonuclease.

Información legal

Technology developed in partnership with Proteome Systems
Proteome Systems is a trademark of Proteome Systems Ltd

pictogramas

Skull and crossbonesHealth hazard

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1

Código de clase de almacenamiento

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificate of Analysis

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Certificate of Origin

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