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A4486

AMPK (α1/β1/γ3), active, His tagged human

Name: AMPK (α1/β1/γ3), active, His tagged human
Brand: SIGMA
Price: 1480 EUR

PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sinónimos:

HAMPKb, MGC17785, MGC33776, MGC57364, PRKAA1, PRKAB1, PRKAG3

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Talla/SKU	Disponibilidad	Precio
10 μg	Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad	1480,00 €

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NACRES:

NA.77

UNSPSC Code:

12352200

Specific activity:

157-213 nmol/min·mg

Assay:

≥70% (SDS-PAGE)

Recombinant:

expressed in baculovirus infected Sf9 cells

1480,00 €

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Propiedades

recombinant

expressed in baculovirus infected Sf9 cells

Quality Segment

200

product line

PRECISIO^® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

157-213 nmol/min·mg

mol wt

A1 subunit ~68 kDa, B1 subunit ~38 kDa, G3 subunit ~51 kDa

UniProt accession no.

Q13131, Q9UGI9, Q9Y478

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PRKAA1(5562), PRKAB1(5564), PRKAG3(53632)

Descripción

Biochem/physiol Actions

AMPK (A1/B1/G3) is a member of the AMPK family which are heterotrimeric proteins consisting of an α catalytic subunit, and non-catalytic β and γ subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress. AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and 3-hydroxy-3-methylglutaryl-CoA reductase. The γ subunit is dominantly expressed in skeletal muscle where it may play a key role in the regulation of energy metabolism.

Physical form

Supplied in 50 mM Sodium Phosphate, pH 7.0, with 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

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Este artículo	A1233	A4611	SRP5003
Sigma-Aldrich A4486 AMPK (α1/β1/γ3), active, His tagged human	Sigma-Aldrich A1233 AMPK (α1/β1/γ1), active, His tagged human	Sigma-Aldrich A4611 AMPK (α1/β2/γ1), active, His tagged human	Sigma-Aldrich SRP5003 AMPK (α2/β2/γ1), active, His tagged human
description PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution	description PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution	description PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution	description PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Gene Information human ... PRKAA1(5562), PRKAB1(5564), PRKAG3(53632)	Gene Information human ... PRKAA1(5562), PRKAB1(5564), PRKAG1(5571)	Gene Information human ... PRKAA1(5562), PRKAB2(5565), PRKAG1(5571)	Gene Information human ... PRKAA2(5563), PRKAB2(5565), PRKAG1(5571)
assay ≥70% (SDS-PAGE)	assay ≥70% (SDS-PAGE)	assay ≥70% (SDS-PAGE)	assay ≥70% (SDS-PAGE)
specific activity 157-213 nmol/min·mg	specific activity 626-848 nmol/min·mg	specific activity 297-401 nmol/min·mg	specific activity 238-322 nmol/min·mg
recombinant expressed in baculovirus infected Sf9 cells	recombinant expressed in baculovirus infected Sf9 cells	recombinant expressed in baculovirus infected Sf9 cells	recombinant expressed in baculovirus infected Sf9 cells
form buffered aqueous glycerol solution	form buffered aqueous glycerol solution	form buffered aqueous glycerol solution	form buffered aqueous glycerol solution
mol wt A1 subunit ~68 kDa, B1 subunit ~38 kDa, G3 subunit ~51 kDa	mol wt A1 subunit ~68 kDa, G1 subunit ~40 kDa, B1 subunit ~38 kDa	mol wt B2 subunit ~36 kDa, G1 subunit ~40 kDa, A1 subunit ~68 kDa	mol wt ~69 kDa (A2), ~36 kDa (B2), ~40 kDa (G1)

Pictogramas

GHS08

Palabra de advertencia

Danger

Códigos de peligro

H360D

Indicaciones de precaución

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

¿Qué está pasando?

WGK 1

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable

Listados normativos

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288-32-4

CAS No.

rmu

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