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C4859

Sigma-Aldrich

Cycloheximide solution

Ready-Made Solution, microbial, 100 mg/mL in DMSO, Suitable for cell culture

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Sinónimos:
CHX
Empirical Formula (Hill Notation):
C15H23NO4
Número de CAS:
66-81-9
Peso molecular:
281.35
Número MDL:
MFCD00082346
ID de la sustancia en PubChem:
24892732
NACRES:
NA.77

origen biológico

microbial

Nivel de calidad

300

descripción

suitable for testing specifications (CHO C. growth inhibitor)

formulario

solution

concentración

100 mg/mL in DMSO

solubilidad

DMSO: soluble

espectro de actividad antibiótica

fungi
yeast

Modo de acción

protein synthesis | interferes

temp. de almacenamiento

2-8°C

SMILES string

O=C1[C@@]([C@H](O)CC2CC(NC(C2)=O)=O)([H])C[C@@H](C)C[C@@H]1C

InChI

1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1

InChI key

YPHMISFOHDHNIV-FSZOTQKASA-N

Gene Information

human ... FKBP1A(2280) , PIN1(5300)

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Este artículo
C769823976546401
Cycloheximide solution Ready-Made Solution, microbial, 100 mg/mL in DMSO, Suitable for cell culture

Sigma-Aldrich

C4859

Cycloheximide solution

Cycloheximide from microbial, ≥94% (TLC)

Sigma-Aldrich

C7698

Cycloheximide

InSolution Cycloheximide Ready-Made Solution, microbial, 100 mg/mL in DMSO, Suitable for cell culture

Sigma-Aldrich

239765

InSolution Cycloheximide

Cycloheximide PESTANAL®, analytical standard

Supelco

46401

Cycloheximide

solubility

DMSO: soluble

solubility

ethanol: soluble, clear to hazy

solubility

-

solubility

H2O: slightly soluble

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

Quality Level

300

Quality Level

200

Quality Level

100

Quality Level

100

biological source

microbial

biological source

microbial

biological source

-

biological source

-

description

suitable for testing specifications (CHO C. growth inhibitor)

description

-

description

-

description

mixture of stereo isomers

Especificidad

Tested for cell growth arrest, selection of cycloheximide resistant yeast, apoptosis induction, and facilitation of apoptosis induction by FasL.

Acciones bioquímicas o fisiológicas

Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors.

Otras notas

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.Hygroscopic. Storage class (TRGS 510): Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials.

pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2

Código de clase de almacenamiento

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Punto de inflamabilidad F

188.6 °F - closed cup

Punto de inflamabilidad C

87 °C - closed cup

Listados normativos

Los listados normativos se proporcionan para los productos químicos principalmente. Para los productos no químicos sólo se puede proporcionar información limitada. Si no hay ninguna entrada, significa que ninguno de los componentes está en la lista. Es obligación del usuario garantizar el uso seguro y legal del producto.

Anexo XVII de REACH de la UE (lista de restricciones)

CAS No.

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Las referencias de los producto se combinan con los tamaños de envase y las cantidades cuando se muestran en la página web, por ejemplo: T1503-25G. Asegúrese de introducir el número de producto ÚNICAMENTE en el campo del Número de producto (Ejemplo T1503).

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T1503
Referencia del producto
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25G
Tamaño del envase/cantidad

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