C7352

Sigma-Aldrich

L-Cysteine

from non-animal source, BioReagent, suitable for cell culture, ≥98%

Sinónimos:
(R)-2-Amino-3-mercaptopropionic acid
Fórmula lineal:
HSCH2CH(NH2)CO2H
Número de CAS:
Peso molecular:
121.16
Beilstein/REAXYS Number:
1721408
Número de EC:
Número MDL:
eCl@ss:
32160406
ID de la sustancia en PubChem:
NACRES:
NA.75

Nivel de calidad

200

origen biológico

non-animal source

línea de producto

BioReagent

ensayo

≥98%

formulario

crystalline powder

aplicaciones

cell culture | mammalian: suitable

impurezas

endotoxin, tested

color

white

mp

240 °C (dec.) (lit.)

solubilidad

H2O: 25 mg/mL

SMILES string

N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1

InChI key

XUJNEKJLAYXESH-REOHCLBHSA-N

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Descripción general

L-Cysteine is one of the sulfur containing proteinogenic amino acid incorporated into proteins as directed by the genetic code. The thiol-side chain participates in a variety of oxidation/reduction reactions within the cell. The side chain participates in the formation of β bonds that modulate the secondary and ternary structure of proteins. L-Cysteine is an essential precursor for inorganic sulfates, coenzyme A. Cysteine is an essential and limiting for the formation of glutathione, an important antioxidant, within the cell. Mammalian liver can synthesize L-cysteine and is a semi-essential amino acid. L-cysteine prevents oxidation of nerve cells, aids in maintaining the stability and rigidity of connective tissues. L-cysteine speeds up the healing process of the body and reduces inflammatory reactions. L-cysteine protects testis partially against acrylamide induced toxicity. L-cysteine can prevent DNA damage during cryopreservation and preserves semen quality.
L-Cysteine is a proteinogenic amino acid incorporated into proteins as directed by the genetic code. The thiol-side chain participates in a variety of oxidation/reduction reactions within the cell. The side chain participates in the formation of β bonds that modulate the secondary and ternary structure of proteins. Cysteine is essential and limiting for the formation of glutathione, an important antioxidant, within the cell.

Aplicación

L-Cysteine has been used:
  • as a media supplement in Trypticase-Yeast Extract-Iron-Serum (TYI-S-33) media for the culture of Giardia lamblia, to make enzyme solution in Dulbecco′s modified Eagles medium (DMEM) to establish hippocampus culture
  • to test its protective effect on acrylamide induced toxicity in testis
  • in the preparation of tris acetic acid extender solution for cryopreservation of semen
  • as an additive to make papain digestion solution

Envase

10 mg in glass bottle
25, 100 g in poly bottle
1 kg in poly bottle

Acciones bioquímicas o fisiológicas

NMDA glutamatergic receptor agonist.

Otras notas

L-Cysteine is used to supplement cell culture media. This product is a non-animal source amino acid useful for serum-free media formulations intended for biomanufacturing applications.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C7352.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

storage_class_code

13 - Non Combustible Solids

WGK Alemania

WGK 1

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Certificado de Análisis

Certificado de origen

Fibroblast growth factor 23 signaling in hippocampal cells: impact on neuronal morphology and synaptic density
Hensel N, et al.
Journal of Neurochemistry, 137(5), 756-769 (2016)
An image-based assay for high throughput screening of Giardia lamblia
Gut J, et al.
Journal of Microbiological Methods, 84(3), 398-405 (2011)
Preparation of rat brain aggregate cultures for neuron and glia development studies
Koito H and Li J
Journal of Visualized Experiments, (31), 1304-1304 (2009)
Effect of L-Cysteine on post thaw quality of Nili Ravi buffalo (Bubalus bubalis) bull spermatozoa cryopreserved in tris citric acid extender
Wadood F, et al.
The Journal of Animal and plant sciences, 25, 301-303 (2015)
L-Cysteine Partially Protects Against Acrylamide-Induced Testicular Toxicity.
Kacar S, et al.
Balkan medical journal, 35(4), 311-311 (2018)
Artículos
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
Más información
Protocolos
Separation of L-Alanine; Glycine; L-Valine; L-Leucine; L-Isoleucine; L-Proline; L-Methionine; L-Serine; L-Threonine; L-Phenylalanine; L-Aspartic acid; L-4-Hydroxyproline; L-Cysteine; L-Glutamic acid; L-Asparagine; L-Lysine; L-Glutamine; L-Histidine; L-Tyrosine; L-Tryptophan; L-Cystine
Más información

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