E3263

Efaroxan hydrochloride

≥98% (HPLC)

• Sinónimos: 2-Ethyl-2-(imidazolin-2-yl)-2,3-dihydrobenzofuran hydrochloride, RX 821037A
• Fórmula empírica (notación de Hill): C₁₃H₁₆N₂O · HCl
• Número CAS: 89197-00-2
• Peso molecular: 252.74
• NACRES: NA.77
• PubChem Substance ID: 24278415
• UNSPSC Code: 12352200
• MDL number: MFCD00069270
• Assay: ≥98% (HPLC)

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• solubility: H₂O: >20 mg/mL
• SMILES string: Cl.CCC1(Cc2ccccc2O1)C3=NCCN3
• InChI: 1S/C13H16N2O.ClH/c1-2-13(12-14-7-8-15-12)9-10-5-3-4-6-11(10)16-13;/h3-6H,2,7-9H2,1H3,(H,14,15);1H
• InChI key: DWOIUCRHVWIHAH-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

Descripción

Biochem/physiol Actions

(+)-Isomer is a selective α-adrenoceptor antagonist; (−)-isomer is an imidazoline ligand that induces insulin secretion, mediated by the blockade of ATP-sensitive potassium channels in pancreatic β cells; I₁ imidazoline binding site antagonist.

(+)-Isomer is a selective α-adrenoceptor antagonist; (−)-isomer is an imidazoline ligand; I₁ imidazoline binding site antagonist.

Features and Benefits

This compound is featured on the Imidazoline Binding Sites and Potassium Channels pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Pictogramas: GHS06
• Palabra de advertencia: Danger
• Códigos de peligro: H301
• Indicaciones de precaución: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges