The stability of this product when prepared in DMSO has not been determined. In general, solutions in DMSO should be prepared fresh and used promptly. Epinephrine is most stable in acidic aqueous solutions at pH 3.6, when stored tightly sealed under nitrogen or argon. Solutions prepared in basic buffers are unstable and turn red in color due to degradation. Published literature indicates solutions are stable for at least 1 month when stored at 4°C or 25°C. Commercial solutions are often assigned a shelf life of greater than 1 year.
E4250
(−)-Epinephrine
≥99% (HPLC), powder, adrenoceptor agonist
Sinónimos:
(−)-Adrenalin, (R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol, L-Adrenaline, L-Epinephrine
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| Talla/SKU | Disponibilidad | Precio |
|---|---|---|
1 g | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 41,30 € |
5 g | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 157,00 € |
10 g | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 246,00 € |
Acerca de este artículo
Fórmula lineal:
(HO)2C6H3CH(OH)CH2NHCH3
Número CAS:
Peso molecular:
183.20
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-098-7
MDL number:
Beilstein/REAXYS Number:
2368277
eCl@ss:
32160703
41,30 €
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
Servicio técnico
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Permítanos ayudarleNombre del producto
(−)-Epinephrine,
Quality Segment
mp
215 °C (dec.) (lit.)
storage temp.
2-8°C
SMILES string
CNC[C@H](O)c1ccc(O)c(O)c1
InChI
1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1
InChI key
UCTWMZQNUQWSLP-VIFPVBQESA-N
Gene Information
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155)
rat ... Adra1a(29412), Adra2a(25083), Adrb1(24925), Adrb2(24176), Drd1a(24316), Drd2(24318)
Biochem/physiol Actions
Adrenoceptor agonist.
Features and Benefits
This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors and β-Adrenoceptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
This product is only slightly soluble in water. Other sources state that it is soluble at 2 mg/mL in DMSO. The product solubility is tested at 50 mg/mL in 0.5 M HCl. This stock concentration can be diluted further in a buffer or medium to the required final concentration. In general, culture medium is buffered such that the final pH is not effected. The compound will remain in solution.
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Este artículo | |||
|---|---|---|---|
| description - | description European Pharmacopoeia (EP) Reference Standard | description CRS, European Pharmacopoeia (EP) Reference Standard | description pkg of 400 mg, certified reference material, pharmaceutical secondary standard |
| Quality Level 200 | Quality Level - | Quality Level - | Quality Level 300 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. -10 to -25°C |
| Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155) | Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155) | Gene Information - | Gene Information - |
| mp 215 °C (dec.) (lit.) | mp 215 °C (dec.) (lit.) | mp 215 °C (dec.) (lit.) | mp 215 °C (dec.) (lit.) |
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Palabra de advertencia
Danger
Clase de almacenamiento
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Punto de inflamación (°F)
Not applicable
Punto de inflamación (°C)
Not applicable
EPI (equipos de protección individual)
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Códigos de peligro
Indicaciones de precaución
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Oral
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When this product is reconstituted in DMSO, at what temperature should it be stored?
1 respuesta-
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Hi, Is it possible to reconstitute the epinephrine solution in something less aggressive than 0.5 M HCl ? Sincerely, Alex
1 respuesta-
This product is only slightly soluble in water. Other sources state that it is soluble at 2 mg/mL in DMSO. The product solubility is tested at 50mg/mL in 0.5 M HCl. This stock concentration can be diluted further in a buffer or medium to the required final concentration. In general, culture medium is buffered such that the final pH is not effected. The compound will remain in solution.
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