E4375

(−)-Epinephrine (+)-bitartrate salt

solid, adrenergic receptor agonist

• Sinónimos: L-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol D-hydrogen bitartrate salt, L-Adrenaline (+)-bitartrate salt, L-Adrenaline D-hydrogentartrate, L-Epinephrine D-hydrogentartrate
• Fórmula empírica (notación de Hill): C₉H₁₃NO₃ · C₄H₆O₆
• Número CAS: 51-42-3
• Peso molecular: 333.29
• NACRES: NA.77
• PubChem Substance ID: 24277774
• UNSPSC Code: 12352200
• EC Number: 200-097-1
• MDL number: MFCD00035077
• Form: solid

Propiedades

• Nombre del producto: (−)-Epinephrine (+)-bitartrate salt, solid
• form: solid
• Quality Segment: 200
• color: white
• solubility: H₂O: soluble, alcohol: soluble
• storage temp.: 2-8°C
• SMILES string: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CNC[C@H](O)c1ccc(O)c(O)c1
• InChI: 1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
• InChI key: YLXIPWWIOISBDD-NDAAPVSOSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155)

Descripción

General description

Epinephrine is a hormone, which is also termed as adrenaline. It is a monoamine and catecholamine.

Application

(-)Epinephrine (+)-bitartrate salt has been used:

• to test the possible existence of β-adrenergic vasodilation
• to infuse into the adipose region to minimize blood loss and tissue contamination
• as a platelet agonist in the preparation of optimal platelet aggregometry 96-well plates
• in the measurement of total superoxide dismutase (tSOD) enzymatic activity

Biochem/physiol Actions

Adrenergic receptor agonist.

Epinephrine is mainly liberated from adrenal medulla in response to stress, that is facilitated through sympathetic fibers.

Features and Benefits

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors, β-Adrenoceptors and Dopamine, Norepinephrine and Epinephrine Synthesis pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

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Información de seguridad

• Pictogramas: GHS06
• Palabra de advertencia: Danger
• Códigos de peligro: H300
• Indicaciones de precaución: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 1 Oral
• Clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges