E6758

Ethylenediaminetetraacetic acid

anhydrous, crystalline, BioReagent, suitable for cell culture

• Synonym(s): (Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid
• Linear Formula: (HO₂CCH₂)₂NCH₂CH₂N(CH₂CO₂H)₂
• CAS Number: 60-00-4
• Molecular Weight: 292.24
• Beilstein: 1716295
• Número de EC: 200-449-4
• Número MDL: MFCD00003541
• eCl@ss: 39030907
• ID de la sustancia en PubChem: 24894634
• NACRES: NA.25

Properties

• grado: anhydrous
• Nivel de calidad: 200
• Línea del producto: BioReagent
• ensayo: ≥98.5%
• formulario: crystalline
• technique(s): cell culture | mammalian: suitable
• mp: 250 °C (dec.) (lit.)
• solubilidad: 3 M NaOH: 100 mg/mL
• densidad: 1.46 g/cm³ at 20 °C
• trazas de catión: C: 40.7-41.5%; N: 9.3-9.8%
• SMILES string: OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O
• InChI: 1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)
• InChI key: KCXVZYZYPLLWCC-UHFFFAOYSA-N

Description

Aplicación

Ethylenediaminetetraacetic acid has been used:

• as a component of peptide dilution buffer for intracellular BH3 (Bcl-2 homology (BH) domain) profiling and validation
• as a medium component in the hepatic stellate cell (HSCs) culture
• as a component of homogenization buffer for protein extraction from eye tissues
• for stopping benzonase reaction in lysis buffer

Acciones bioquímicas o fisiológicas

Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood samples. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline imparts serves as root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium Disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.

Safety Information

• pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H319
• Consejos de prudencia: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Clasificaciones de peligro: Eye Irrit. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 2
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves