L1663

Lidocaine N-ethyl chloride

Name: Lidocaine N-ethyl chloride
Brand: SIGMA

sodium channel blocker

Sinónimos:

N-(2,6-Dimethylphenylcarbamoylmethyl) triethylammonium chloride

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Fórmula empírica (notación de Hill):

C₁₆H₂₇N₂OCl

Número CAS:

5369-03-9

Peso molecular:

298.85

UNSPSC Code:

12352200

PubChem Substance ID:

24896288

NACRES:

NA.77

MDL number:

MFCD01669894

Quality level:

100

Storage condition:

protect from light

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Nombre del producto

Lidocaine N-ethyl chloride,

storage condition

protect from light

Quality Level

100

solubility

H₂O: soluble

storage temp.

room temp

SMILES string

[Cl-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C16H26N2O.ClH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H

InChI key

LLPPOMUAOGMYQI-UHFFFAOYSA-N

Categorías relacionadas

Bioactive Small Molecules

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Este artículo	SML1444	C4382	D2926
Sigma-Aldrich L1663 Lidocaine N-ethyl chloride	Sigma-Aldrich SML1444 (±)-Mepivacaine hydrochloride	Sigma-Aldrich C4382 Carbamoylcholine chloride	Sigma-Aldrich D2926 Diphenyleneiodonium chloride
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 300
storage temp. room temp	storage temp. room temp	storage temp. -	storage temp. room temp
solubility H₂O: soluble	solubility H₂O: 20 mg/mL, clear	solubility H₂O: 1 g/mL, ethanol: 20 mg/mL	solubility DMSO: 9.80-10.20 mg/mL, clear, colorless to faintly yellow
storage condition protect from light	storage condition desiccated	storage condition -	storage condition -

Biochem/physiol Actions

Lidocaine N-ethyl chloride is an intracellular voltage-gated sodium channel blocker.

Other Notes

Stable at room temperature lyophilized. In solution, store at 4 °C for up to two weeks. Store solutions at -20 °C for up to six months.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Biomolecules, 10(11) (2020-11-11)

Local anesthetics (LAs) can completely block nociception by inhibiting voltage-gated sodium channels (VGSCs), and thus, blocking action potentials (APs) within sensory neurons. As one of the several LAs, eugenol is used for dental pain treatment. It reportedly features multiple functions

Asymmetry between ON and OFF α ganglion cells of mouse retina: integration of signal and noise from synaptic inputs.

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The Journal of physiology, 595(22), 6979-6991 (2017-09-16)

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Functional Voltage-Gated Calcium Channels Are Present in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium.

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Retinal pigment epithelium (RPE) performs important functions for the maintenance of photoreceptors and vision. Malfunctions within the RPE are implicated in several retinal diseases for which transplantations of stem cell-derived RPE are promising treatment options. Their success, however, is largely

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Número de artículo de comercio global

SKU	GTIN
L1663-500MG	04061832574783
L1663-1G	04061826226247

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