M2017

Mazindol

≥98% (TLC), powder

• Sinónimos: 5-(4-Chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol
• Fórmula empírica (notación de Hill): C₁₆H₁₃ClN₂O
• Número CAS: 22232-71-9
• Peso molecular: 284.74
• NACRES: NA.77
• PubChem Substance ID: 24896596
• UNSPSC Code: 12352200
• EC Number: 244-857-0
• MDL number: MFCD00864480
• Assay: ≥98% (TLC)
• Form: powder

Propiedades

• assay: ≥98% (TLC)
• form: powder
• drug control: USDEA Schedule IV; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland
• color: white
• solubility: DMSO: 10 mg/mL
• originator: Wyeth
• SMILES string: OC1(C2=CC=C(Cl)C=C2)C3=CC=CC=C3C4=NCCN14
• InChI: 1S/C16H13ClN2O/c17-12-7-5-11(6-8-12)16(20)14-4-2-1-3-13(14)15-18-9-10-19(15)16/h1-8,20H,9-10H2
• InChI key: ZPXSCAKFGYXMGA-UHFFFAOYSA-N
• Gene Information: human ... SLC6A2(6530), SLC6A3(6531), SLC6A4(6532) ; rat ... Htr1a(24473), Htr2a(29595), Slc6a3(24898), Slc6a4(25553)

Descripción

Biochem/physiol Actions

Anorectic agent; inhibits the dopamine, norepinephrine and serotonin transporters with K_is of 27.6 nM, 3.2 nM, and 153 nM, respectively.

Anorectic agent; inhibits the dopamine, norepinephrine and serotonin transporters.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

Información de seguridad

• Pictogramas: GHS06
• Palabra de advertencia: Danger
• Códigos de peligro: H300,H311 + H331
• Indicaciones de precaución: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation
• Clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• ¿Qué está pasando?: WGK 3
• EPI (equipos de protección individual): Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges