The N-TER Nanoparticle siRNA Transfection System is a peptide-based system for use in the transient knockdown of eukaryotic gene expression. The N-TER Peptide binds siRNAs non-covalently, forming a nanoparticle. This nanoparticle interacts directly with lipids on the surface of the plasma membrane, allowing the nanoparticle to diffuse across the cell membrane and deliver the siRNA directly to the cytoplasm. Unlike most lipid-based transfection methods, this novel delivery mechanism bypasses the endosomal pathway, eliminating possible compartmentalization and degradation of the siRNA.
Legal Information
Manufactured and Distributed by Sigma-Aldrich, under license from the CNRS.
N-TER is a trademark of Sigma-Aldrich Co. LLC
Clase de almacenamiento
12 - Non Combustible Liquids
WGK
nwg
Punto de inflamación (°F)
Not applicable
Punto de inflamación (°C)
Not applicable
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