P152

S(–)-Pindolol

solid

• Fórmula empírica (notación de Hill): C₁₄H₂₀N₂O₂
• Número CAS: 26328-11-0
• Peso molecular: 248.32
• UNSPSC Code: 12352202
• PubChem Substance ID: 24278026
• MDL number: MFCD00153863
• Form: solid

Propiedades

• form: solid
• Quality Segment: 100
• optical activity: [α]23/D −4.38°, c = 1% in methanol(lit.)
• color: white
• solubility: 0.1 M NaOH: 0.2 mg/mL, methanol: 18 mg/mL, 0.1 M HCl: 20 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 3.4 mg/mL, H₂O: insoluble
• originator: Novartis
• SMILES string: CC(C)NC[C@H](O)COc1cccc2[nH]ccc12
• InChI: 1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3/t11-/m0/s1
• InChI key: JZQKKSLKJUAGIC-NSHDSACASA-N
• Gene Information: human ... ADRB1(153), HTR1A(3350), HTR1B(3351)

Descripción

Biochem/physiol Actions

β₁-adrenoceptor antagonist; putative 5-HT_1A serotonin receptor agonist; vasodilator. Active enantiomer of pindolol.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): Eyeshields, Gloves, type N95 (US)