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RAB0797

Sigma-Aldrich

Mouse IgA ELISA Kit

NACRES:
NA.32

species reactivity

mouse

technique(s)

ELISA: suitable

assay range

inter-assay cv: <10%
intra-assay cv: <12%

enviado en

wet ice

temp. de almacenamiento

−20°C

Descripción general

The antibody pair provided in this kit recognizes Mouse IgA.

Aplicación

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Acciones bioquímicas o fisiológicas

Immunoglobulin A (IgA) is majorly found in the mucosal secretions. IgA exists as two subclasses, IgA1 and IgA2. IgA is a dimer in animals, but a monomer in humans. IgA interacts with the Fc fragment of IgA receptor (FCAR) to elicit immune response against inhaled pathogens. Secretory IgA (S-IgA) produced by B1 lymphocytes triggers phagocytosis and leucocyte respiratory burst. S-IgA exists as a polymer and is crucial for primary defense. The high levels of IgA in human milk and colostrum may provide immune protection to infants. Deficiency of IgA leads to increased susceptibility to infections. High levels of IgA in kidney is present in IgA nephropathy and IgA myeloma. Autoantibodies of IgA is present in celiac disease.

Otras notas

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)

  • RABSTOP3ELISA Stop Solution (Item I)

  • RABWASH420X Wash Buffer (Item B)

pictogramas

Corrosion

Palabra de señalización

Warning

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Met. Corr. 1

Código de clase de almacenamiento

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificado de Análisis

Certificado de origen

Liqing Huang et al.
Probiotics and antimicrobial proteins, 11(3), 946-956 (2018-06-28)
The effects of Enterococcus faecium on growth, intestinal barrier function, and immune response in Escherichia coli O78-challenged broiler chickens were investigated. Three hundred eight 1-day-old Ross male chickens were randomly assigned into three treatment groups: negative control (C), E. coli
T Gupalova et al.
PloS one, 13(5), e0196564-e0196564 (2018-05-05)
Streptococcus agalactiae, or group B streptococcus (GBS), is an important pathogen as it is the leading cause of neonatal deaths due to sepsis, meningitis or bacterial pneumonia. Although the development of an effective and safe GBS vaccine is on the
Yiran Wang et al.
Molecular immunology, 112, 305-311 (2019-06-24)
The pathophysiology of type II diabetes (T2D) in patients with normal body-mass index (BMI) remains unclear. In this study, we investigated the circulating CD4+CXCR5+ T cells in lean T2D patients. Compared with age-, gender-, and BMI-matched healthy controls, the lean
Chise Suzuki et al.
PloS one, 12(12), e0188985-e0188985 (2017-12-09)
The molecular mechanisms of strain-specific probiotic effects and the impact of the oral administration of probiotic strains on the host's gene expression are not yet well understood. The aim of this study was to investigate the strain-specific effects of probiotic
Function of immunoglobulin A in immunity
Kerr, MA
Gut, 47(6), 751-752 (2000)

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