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S1763

Somatostatin

powder, BioReagent, suitable for cell culture

Sinónimos:

Growth hormone release inhibiting factor, SRIF, Somatostatin-14, Somatotropin release inhibiting factor

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Talla/SKUDisponibilidadPrecio
0.1 mg
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57,20 €
1 mg
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253,00 €

Acerca de este artículo

Fórmula empírica (notación de Hill):
C76H104N18O19S2
Número CAS:
Peso molecular:
1637.88
UNSPSC Code:
12352209
NACRES:
NA.77
PubChem Substance ID:
EC Number:
254-186-5
Beilstein/REAXYS Number:
6436064
MDL number:
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥97% (HPLC)

57,20 €


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biological source

synthetic (organic)

Quality Segment

product line

BioReagent

assay

≥97% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

[H]N1[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc6ccccc6)C(=O)N[C@@H]([C@@H](C)O)C(=O)NC(CO)C(=O)N[C@@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](C)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C1=O)C(O)=O

InChI

1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57?,58-,59-,62-,63-/m0/s1

InChI key

NHXLMOGPVYXJNR-FQSIDJEASA-N

Application

Somatostatin has been used in cell culture. It has also been used in the study of glucose-6-phosphate dehydrogenase activity in monolayer cultures of thyroid epithelial cells.

Biochem/physiol Actions

Somatostatin regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.
Somatostatin (SST) is a peptide. It performs several functions like anti-proliferation, pro-apoptosis and anti-migration. Somatostatin performs physiological activities with the help of various G protein-coupled receptor subtypes (SST receptor (SSTR)-1, SSTR2A, SSTR2B, and SSTR3–5).

Physical form

powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw

Preparation Note

To prepare 2 μg/ml stock solution, dissolve in 5 ml sterile culture medium per μg somatostatin.

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description

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biological source

synthetic (organic)

biological source

-

biological source

rabbit

biological source

rabbit

assay

≥97% (HPLC)

assay

-

assay

-

assay

-

Quality Level

200

Quality Level

-

Quality Level

100

Quality Level

100

product line

BioReagent

product line

-

product line

-

product line

Prestige Antibodies® Powered by Atlas Antibodies

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

immunohistochemistry: suitable (paraffin)

technique(s)

immunoblotting: 0.04-0.4 μg/mL, immunofluorescence: 0.25-2 μg/mL, immunohistochemistry: 1:50-1:200

form

powder

form

-

form

-

form

buffered aqueous glycerol solution


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Clase de almacenamiento

11 - Combustible Solids

¿Qué está pasando?

WGK 3

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable

EPI (equipos de protección individual)

Eyeshields, Gloves, type N95 (US)



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Preguntas

1–3 de 3 Preguntas  
  1. こちらの製品を溶解後-20℃に凍結保存した場合、どれほどの期間安定(使用可能)か情報がございましたら教えてください。 よろしくお願いいたします。

    1 respuesta
    1. This product is soluble in water at 1mg/mL. Working aliquots may be stored at -20°C. Avoid repeated freeze/thaw cycles.
      Long-term stability studies have not been performed. However, various sources state the this compound is stable in solution at 4°C several days and may be stored frozen for extended periods with the addition of a carrier protein (HSA or BSA) at 0.1%. This information has not been validated.

      ¿Le ha resultado útil?

  2. Do I need to filter it after reconstituting it in sterile water?

    1 respuesta
    1. This is not a sterile powder. Stock solutions should be filter sterilized prior to use.

      ¿Le ha resultado útil?

  3. Can I reconstitute Somatostatin in sterile water or PBS?

    1 respuesta
    1. This product can be reconstituted in sterile water at 1mg/mL. While it is very likely soluble at this rate in PBS as well, we have not tested the product to confirm.

      ¿Le ha resultado útil?

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