SML0807

PreQ1 dihydrochloride

≥98% (HPLC), PreQ1 riboswitch regulator, powder

• Sinónimos: 2-Amino-5-(aminomethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one dihydrochloride, 7-Aminomethyl-7-deazaguanine dihydrochloride, Pre-queuosine1 dihydrochloride
• Fórmula empírica (notación de Hill): C₇H₉N₅O · 2HCl
• Número CAS: 86694-45-3
• Peso molecular: 252.10
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Propiedades

• Nombre del producto: PreQ1 dihydrochloride, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to light brown
• solubility: DMSO: 5 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: Cl.Cl.[nH]1c2nc([nH][c](c2c(c1)CN)=O)N
• InChI key: WUMBRQKOLVTYTB-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

PreQ1 (pre-queuosine1) is an intermediate of the queuosine pathway. Also, PreQ1 binds with high affinity to the aptamer of PreQ1 riboswitch, which attenuates protein expression.

PreQ1 (pre-queuosine1), an intermediate of the queuosine pathway, regulates the PreQ1 riboswitch.

PreQ1 is a nucleobase derived from guanine and a precursor of the modified base queuosine that is present in four tRNAs. Prequeuosine (preQ1) riboswitches are RNA regulatory elements present in the 5′ UTR of genes that participates in the biosynthesis and transport of preQ1.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Información de seguridad

• Pictogramas: GHS07
• Palabra de advertencia: Warning
• Códigos de peligro: H302,H315,H319,H335
• Indicaciones de precaución: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos diana: Respiratory system
• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable