SML2199

L-F001

≥98% (HPLC)

• Sinónimos: 5-(3R)-1,2-Dithiolan-3-yl-1-[hexahydro-4-(5-isoquinolinylsulfonyl)-1H-1,4-diazepin-1-yl]-1-pentanone
• Fórmula empírica (notación de Hill): C₂₂H₂₉N₃O₃S₃
• Número CAS: 1715039-50-1
• Peso molecular: 479.68
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: oil
• Storage condition: desiccated

Propiedades

• assay: ≥98% (HPLC)
• form: oil
• storage condition: desiccated
• color: colorless to light brown
• storage temp.: 2-8°C
• SMILES string: O=C(CCCC[C@@H]1CCSS1)N2CCN(S(C3=CC=CC4=C3C=CN=C4)(=O)=O)CCC2
• InChI: 1S/C22H29N3O3S3/c26-22(8-2-1-6-19-10-16-29-30-19)24-12-4-13-25(15-14-24)31(27,28)21-7-3-5-18-17-23-11-9-20(18)21/h3,5,7,9,11,17,19H,1-2,4,6,8,10,12-16H2/t19-/m1/s1
• InChI key: NWTRUKNNHUXONB-LJQANCHMSA-N

Descripción

Biochem/physiol Actions

L-F001 is a multifunctional, brain penetrant and potent Rho-associated protein kinase (ROCK) inhibitor that protects the PC12 cells from paraquat induced cytotoxicity. L-F001 suppresses neuroinflammation in vitro and in vivo.

multifunctional, brain penetrant and potent Rho-associated protein kinase (ROCK) inhibitor

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable