SML2210

AubipyOMe

≥97% (NMR)

• Sinónimos: (SP-4-2)-dichloro(4,4′-dimethoxy-2,2′-bipyridine-kN1,kN1′)-Gold(1+), hexafluorophosphate(1-), [Au(4,4′-dimethoxy-2,2′-bipyridine)Cl2][PF6]
• Fórmula empírica (notación de Hill): C₁₂H₁₂AuCl₂N₂O₂ · PF₆
• Número CAS: 1221591-26-9
• Peso molecular: 629.07
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥97% (NMR)
• Form: powder

Propiedades

• assay: ≥97% (NMR)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [Cl-][Au+3]1([N]2=C(C=C(C=C2)OC)C3=[N]1C=CC(OC)=C3)[Cl-].F[P-](F)(F)(F)(F)F

Descripción

Biochem/physiol Actions

AubipyOMe is a potent inhibitor of tartrate resistant acid phosphatase (TRAP/ACP5), a metalloenzyme expressed in activated osteoclasts and in macrophages. AubipyOMe exhibited IC50 values of 1.3 μM for TRAP5a and 1.8 μM for TRAP5b and inhibited TRAP activity in murine macrophage and human lung tissue extracts.

Tartrate resistant acid phosphatase (TRAP/ACP5) inhibitor

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable