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Merck

ANGPT1

angiopoietin 1

Synonyms:
AGP1, AGPT, ANG1
Species:
UniProtKB ID:
Gene ID:
  • Human(284) Summary: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010]
  • Mouse(11600) angiopoietin 1
  • Rat(89807) angiopoietin 1
  • domestic cat(101087130) angiopoietin 1
  • Zebrafish(114407) angiopoietin 1
  • sheep(497271) angiopoietin 1
  • Horse(100056482) angiopoietin 1
  • cow(282140) angiopoietin 1
  • domestic guinea pig(100716420) angiopoietin 1
  • naked mole-rat(101725800) angiopoietin 1
  • chicken(395129) angiopoietin 1
  • dog(403656) angiopoietin 1

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Angiopoietin-1 Antibody, from rabbit,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rat
Application
western blot
Anti-Angiopoietin-1 Antibody, NT, Chemicon®, from rabbit,
Species Reactivity
mouse
Application
ELISA
western blot