KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
Synonyms:
CD309, FLK1, VEGFR, VEGFR2
Species:
Human KDR (3791), Mouse Kdr (16542), Rat Kdr (25589), chicken KDR (395323), Zebrafish kdr (554230), Thale Cress KDR (839585), dog KDR (482154), Goat KDR (100860836), cow KDR (407170), Horse KDR (100033959) ...More
UniProtKB ID:
Gene ID:
- Human(3791) Summary: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
- Mouse(16542) kinase insert domain protein receptor
- Rat(25589) kinase insert domain receptor
- chicken(395323) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Zebrafish(554230) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Thale Cress(839585) basic helix-loop-helix protein KIDARI
- dog(482154) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Goat(100860836) kinase insert domain receptor (a type III receptor tyrosine kinase)
- cow(407170) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Horse(100033959) kinase insert domain receptor (a type III receptor tyrosine kinase)
- domestic cat(101090260) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Domestic Rabbit(100008607) kinase insert domain receptor (a type III receptor tyrosine kinase)
- sheep(443087) vascular endothelial growth factor receptor-2
- naked mole-rat(101726029) kinase insert domain receptor (a type III receptor tyrosine kinase)
- domestic guinea pig(100726761) kinase insert domain receptor (a type III receptor tyrosine kinase)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-VEGFR2/Flk-1/KDR (Tyr1054) Antibody, Upstate®, from rabbit,
Species Reactivity
danio, bovine, chicken, horse, human, mouse, primate, rat, zebrafish
Application
western blot
Anti-phospho-KDR/Flk-1/VEGFR2 (Tyr1054) Antibody, clone D1W, rabbit monoclonal, culture supernatant, clone D1W, Upstate®,
Species Reactivity
human, mouse
Application
western blot
Anti-KDR/Flk-1/VEGFR2 Antibody, clone CH-11, clone CH-11, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-phospho-KDR/Flk-1/VEGFR2 (Tyr1214) Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse
Application
western blot
Anti-phospho KDR/FLK-1/VEGFR2 Antibody (Tyr1059), from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, canine, chicken, human, mouse, sheep, zebrafish
Application
inhibition assay
western blot
western blot
Proteins
Product Number
Description
Species
KDR Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant, human KDR amino acids 790-end,
for use in Kinase Assays.,
for use in Kinase Assays.,
Species
human