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Merck

804592

Bovine Collagen Solution

Type I, 3 mg/mL, ≥95%, sterile filtered, BSE-Free, suitable for biomedical research

Synonym(s):

Collagen I

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20 ML

€665.00

€665.00


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About This Item

CAS Number:
MDL number:
NACRES:
NA.23
UNSPSC Code:
12162002

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Product Name

Bovine Collagen Solution, Type I, 3 mg/mL, ≥95%, sterile filtered, BSE-Free, suitable for biomedical research

assay

≥95%

form

liquid

concentration

3 mg/mL

shipped in

wet ice

storage temp.

2-8°C

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1 of 4

This Item
804614934070934097
assay

≥95%

assay

-

assay

-

assay

-

form

liquid

form

liquid

form

liquid

form

powder

concentration

3 mg/mL

concentration

6 mg/mL

concentration

-

concentration

-

shipped in

wet ice

shipped in

wet ice

shipped in

-

shipped in

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

Application

Forms a gel at pH 7 and is ideal for 3D biomaterial scaffolds for cell culture, engineering tissue,[1] and drug delivery.[2][3]

General description

  • Highly purified bovine corium pepsin solubilized collagen, atelo collagen, in 0.01 N HCl, pH 2. Predominantly Type I collagen with approximately 5% Type III at 3 mg/ml.
  • Sterile filtered.
  • BSE-Free.
  • ≥95% purity by SDS PAGE.
Bovine Collagen Solution can be used to form 3D structures for culturing or coating plastic labware for increased cell adhesion. It can form a gel at pH 7 and is ideal for 3D biomaterial scaffolds for cell culture, engineering tissue, and drug delivery.

Legal Information

Product of Collagen Solutions.

Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Wallace D, et al.
Advanced Drug Delivery Reviews, 55, 1631-1649 (2003)
Bareil RP, et al.
Materials, 3, 1863-1887 (2010)
Luo Z, et al.
Angewandte Chemie (International Edition in English), 50, 640-643 (2011)
Qun Zhang et al.
Stem cell research & therapy, 11(1), 407-407 (2020-09-20)
In recent years, significant progress has been made in developing highly complex tissue-engineered skin substitutes (TESSs) for wound healing. However, the lack of skin appendages, such as hair follicles and sweat glands, and the time required, are two major limitations
David Olagnier et al.
Nature communications, 11(1), 4938-4938 (2020-10-04)
Antiviral strategies to inhibit Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and the pathogenic consequences of COVID-19 are urgently required. Here, we demonstrate that the NRF2 antioxidant gene expression pathway is suppressed in biopsies obtained from COVID-19 patients. Further, we

Articles

Collagen-based delivery systems effectively deliver a range of viral and non-viral gene carriers by providing spatiotemporal control over delivery and reducing degradation rates and immune responses.

Engineered ECMs enhance immune therapy in cancer treatment by supporting cells and tissues and modulating immune response. They improve immune cell maturation, expansion, and regulation through biomaterial manipulation, acting as frameworks or carriers for enhanced tumor immunotherapy.

Highlighting existing and novel fabrication methods for both, solid and hydrogel-based scaffold for tissue engineering applications.

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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