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901594

Diisopropylcarbodiimide solution

1 M in THF

Synonym(s):

Diisopropylmethanediimine

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100 ML

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About This Item

Linear Formula:
C7H14N2
CAS Number:
693-13-0
MDL number:
MFCD00065689
UNSPSC Code:
12352111
NACRES:
NA.22

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form

liquid

reaction suitability

reaction type: Coupling Reactions

concentration

1 M in THF

density

0.870 g/mL

application(s)

peptide synthesis

SMILES string

N(=C=NC(C)C)C(C)C

InChI

1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3

InChI key

BDNKZNFMNDZQMI-UHFFFAOYSA-N

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This Item
G15224760888185
Diisopropylcarbodiimide solution 1 M in THF

Sigma-Aldrich

901594

Diisopropylcarbodiimide solution

Gentamicin solution Hybri-Max™, 50 mg/mL gentamicin, 0.1 μm filtered, BioReagent, suitable for hybridoma

Sigma-Aldrich

G1522

Gentamicin solution

Formaldehyde solution Molecular Biology, BioReagent, ≥36.0% in H2O (T)

Sigma-Aldrich

47608

Formaldehyde solution

Tetrazole solution suitable for DNA synthesis, filtered through a 1 μm filter, ~0.45 M in acetonitrile

Sigma-Aldrich

88185

Tetrazole solution

form

liquid

form

liquid

form

liquid

form

liquid

reaction suitability

reaction type: Coupling Reactions

reaction suitability

-

reaction suitability

-

reaction suitability

-

concentration

1 M in THF

concentration

50 mg/mL gentamicin

concentration

≥36.0% in H2O (T), 36.0-38.0% (aldehyde method)

concentration

~0.45 M in acetonitrile

density

0.870 g/mL

density

1.000 g/cm3

density

1.09 g/mL at 20 °C, 1.09 g/mL at 25 °C (lit.)

density

0.798 g/mL at 20 °C

application(s)

peptide synthesis

application(s)

-

application(s)

-

application(s)

-

Application

Coupling reagent for peptide syntheses.[1][2][3]
DIC (N,N′-Diisopropylcarbodiimide) has been used in combination with 1-hydroxy-7-azabenzotriazole (HOAt) for the coupling of amino acid with N-allylglycine to form N-allylpeptide.[4]
Valuable reagent offered as a solution in tetrahydrofuran for more convenient handling.

comparable product

Product No.
Description
Pricing

38370

DIC, purum, ≥98.0% (GC)

D125407

DIC, 99%

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Resp. Sens. 1 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

2.0 °F

Flash Point(C)

-16.66 °C

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX5315
MKCG2872
MKCW1383
MKCR3315

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Tetrahedron Letters, 35, 5981-5981 (1994)
Collection of Czechoslovak Chemical Communications, 59, 691-691 (1994)
Stéphane Chantepie et al.
PloS one, 10(7), e0133140-e0133140 (2015-07-29)
Do all traits within an organism age for the same reason? Evolutionary theories of aging share a common assumption: the strength of natural selection declines with age. A corollary is that additive genetic variance should increase with age. However, not
Cody L Gilleland et al.
Genetics, 201(1), 39-46 (2015-07-15)
A major goal in the study of human diseases is to assign functions to genes or genetic variants. The model organism Caenorhabditis elegans provides a powerful tool because homologs of many human genes are identifiable, and large collections of genetic
P J Weber et al.
Bioorganic & medicinal chemistry letters, 8(6), 597-600 (1999-01-01)
A new method has been developed to synthesize fluorescein labeled peptides, compounds of increasing importance in bioorganic chemistry, cell biology, pharmacology, drug targeting and medicinal chemistry. We show, that 4(5)-carboxyfluorescein is much more efficient than the hitherto predominantly utilized reagents
View All Related Papers

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