Skip to Content
Merck

1.59002

Acetonitrile solution

suitable for LC/MS, LiChrosolv®, contains 0.1% (v/v) formic acid

Synonym(s):

Acetonitrile solution, ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide

Sign In to View Organizational & Contract Pricing

Select a Size

1 L

€122.00

2.5 L

€263.00

4 L

€417.00

€122.00


Estimated to ship onDecember 17, 2025Details


Request a Bulk Order

About This Item

Linear Formula:
CH3CN
CAS Number:
Molecular Weight:
41.05
Beilstein:
4124158
MDL number:
UNSPSC Code:
41116004
NACRES:
NA.03
Technique(s):
HPLC: suitable
LC/MS: suitable
Application(s):
general analytical
Bp:
81.6 °C/1,013 hPa
Vapor pressure:
97 hPa ( 20 °C)

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Acetonitrile with 0.1% (v/v) Formic acid, hypergrade for LC-MS LiChrosolv®

vapor pressure

97 hPa ( 20 °C)

Quality Level

product line

LiChrosolv®

form

liquid

expl. lim.

3.0-17 % v()

concentration

0.095-0.105 % (v/v)

technique(s)

HPLC: suitable
LC/MS: suitable

bp

81.6 °C/1,013 hPa

mp

-45.7 °C (-50.3 °F)

transition temp

flash point 2 °C

solubility

water: soluble

density

0.782 g/mL at 25 °C

cation traces

Al: ≤0.05 ppm
Ca: ≤0.05 ppm
Fe: ≤0.05 ppm
K: ≤0.025 ppm
Mg: ≤0.05 ppm
Na: ≤0.25 ppm

application(s)

general analytical

format

mixture

storage temp.

2-30°C

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
4.804481.000291.59014
application(s)

general analytical

application(s)

-

application(s)

-

application(s)

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

technique(s)

LC/MS: suitable

technique(s)

HPLC: suitable

technique(s)

LC/MS: suitable

technique(s)

LC/MS: suitable

solubility

water: soluble

solubility

-

solubility

-

solubility

-

form

liquid

form

liquid

form

liquid

form

liquid

vapor pressure

97 hPa ( 20 °C)

vapor pressure

97 hPa ( 20 °C)

vapor pressure

72.8 mmHg ( 20 °C), 97 hPa ( 20 °C)

vapor pressure

97 hPa ( 20 °C)

General description

For fast chromatography and LC-MS detection, LiChrosolv® hypergrade, a family of solvents especially optimized and tested for LC-MS suitability is most suitable. LiChrosolv® hypergrade solvents meet all the requirements of modern LC-MS ionization methods (ESI/ APCI – positive and negative mode). Due to their low level of ionic background and low ion suppression, LiChrosolv® hypergrade solvents ensure high reproducibility and high ionization efficiency.

Application

LiChrosolv® hypergrade acetonitrile with 0.1% (v/v) formic acid is used as a mobile phase solvent in gradient elution of peptides by LC-MS/MS.[1][2][3]
The product is also featured in the method development for analysis of California list of pesticides in cannabis.

Features and Benefits

  • microfiltered by 0.2 µm filter
  • the most comprehensive application range due to the largest retention time range
  • analytical reliability due to the highest possible purity and a minimum signal-to-noise ratio
  • time and cost savings due to the best possible batch consistency, thus avoiding repetitive analysis

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - (refers to pure substance)

Flash Point(C)

2 °C - (refers to pure substance)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins
Alzahofi N, et al.
Nature Communications, 11(1), 1-21 (2020)
The stereospecific interaction sites and target specificity of cGMP analogs in mouse cortex
Rasmussen M, et al.
Chemical Biology & Drug Design, 99(2), 206-221 (2022)
The cGMP system in normal and degenerating mouse neuroretina: New proteins with cGMP interaction potential identified by a proteomics approach
Rasmussen M, et al.
Journal of Neurochemistry, 157(6), 2173-2186 (2021)

Articles

Complete workflow for cannabis flower pesticide testing using LC-MS/MS and GC-MS/MS ensures product safety.

Learn the tips and tricks of selecting and preparing a suitable mobile phase buffer for your HPLC separations and method developments for samples that contain ionizable compounds.

An optimized peptide mapping protocol using NISTmAb as a model monoclonal antibody, shorter incubation times, and improved digestion buffer to demonstrate minimal artificial asparagine deamidation and methionine oxidation.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service