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Merck

400120

Human IgG1, Myeloma

Synonym(s):

Myeloma IgG₁

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2 MG

€323.00

€323.00


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About This Item

NACRES:
NA.32
UNSPSC Code:
12352202

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assay

>95% (SDS-PAGE)

form

liquid

contains

≤0.1% sodium azide as preservative

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

shipped in

wet ice

storage temp.

−20°C

Quality Level

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This Item
I5404I5154400109
form

liquid

form

-

form

-

form

liquid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

wet ice

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

Calbiochem®

assay

>95% (SDS-PAGE)

assay

>95% (SDS-PAGE)

assay

>95% (SDS-PAGE)

assay

>97% (SDS-PAGE)

contains

≤0.1% sodium azide as preservative

contains

-

contains

-

contains

≤0.1% sodium azide as preservative

Disclaimer

Toxicity: Standard Handling (A)

General description

Native IgG1 from human myeloma plasma. Purified from plasma of patients with myelomas producing IgG1 with kappa light chains.

Other Notes

Single arc by immunoelectrophoresis against antiserum to whole human sera and human κ free and bound light chain. Note: the heavy chain of myeloma IgGs may appear as either a single or double band on gel electrophoresis. Variables associated with assay conditions will dictate the proper working dilution.

Physical form

In 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.

Preparation Note

Prepared from plasma that was shown by certified tests to be negative for HBsAg and for antibodies to HCV, HBc, HIV-1 and HIV-2.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Anna Moroz et al.
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Lili Huang et al.
Journal of leukocyte biology, 80(4), 905-914 (2006-08-05)
LFA-1 (alpha(L)beta(2)) mediates cell-cell and cell-extracellular matrix adhesions essential for immune and inflammatory responses. One critical mechanism regulating LFA-1 activity is the conformational change of the ligand-binding alpha(L) I domain from low-affinity (LA), closed form, to the high-affinity (HA), open
Liliane Khoryati et al.
Arthritis & rheumatology (Hoboken, N.J.), 68(9), 2221-2231 (2016-03-19)
Plasmacytoid dendritic cells (PDCs) play a central role in pathogenesis of systemic lupus erythematosus (SLE) through their unique ability to produce large amounts of type I interferon (IFN) upon Toll-like receptor 7 (TLR-7) and TLR-9 triggering. PDCs express specific surface
R B Cejas et al.
Scientific reports, 11(1), 10981-10981 (2021-05-28)
Persons with Down syndrome (DS, trisomy 21) have widespread cellular protein trafficking defects. There is a paucity of data describing the intracellular transport of IgG in the context of endosomal-lysosomal alterations linked to trisomy 21. In this study, we analyzed
Jorg C de Ruijter et al.
FEMS yeast research, 17(1) (2016-12-14)
Cost-effective manufacturing of biopharmaceuticals in non-mammalian hosts still requires tremendous efforts in strain development. In order to expedite identification of novel leads for strain engineering, we used a transposon-mutagenized yeast genomic DNA library to create a collection of Saccharomyces cerevisiae

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