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Merck

G2299

L-Glutathione oxidized

Synonym(s):

GSSG, Glutathiol

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100 G

€1,280.00

1 KG

€8,420.00

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About This Item

Empirical Formula (Hill Notation):
C20H32N6O12S2
CAS Number:
27025-41-8
Molecular Weight:
612.63
Beilstein:
1718700
EC Number:
248-170-7
MDL number:
MFCD00063106
UNSPSC Code:
12352209
NACRES:
NA.21

Key Documents

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biological source

synthetic

Quality Level

400

form

powder

solubility

H2O: 10 mg/mL, clear, colorless

suitability

suitable for manufacturing use

storage temp.

2-8°C

SMILES string

N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1

InChI key

YPZRWBKMTBYPTK-BJDJZHNGSA-N

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Show Differences

1 of 4

This Item
G4376G66543542
L-Glutathione oxidized

SAFC

G2299

L-Glutathione oxidized

L-Glutathione oxidized ≥98% (HPLC)

Sigma-Aldrich

G4376

L-Glutathione oxidized

L-Glutathione oxidized BioXtra, ≥98%

Sigma-Aldrich

G6654

L-Glutathione oxidized

Glutathione, Oxidized, Free Acid Glutathione, Oxidized, Free Acid, CAS 27025-41-8, forms a "redox buffer" in physiological systems in the presence of reduced glutathione.

Sigma-Aldrich

3542

Glutathione, Oxidized, Free Acid

form

powder

form

powder

form

powder

form

solid

biological source

synthetic

biological source

-

biological source

-

biological source

-

suitability

suitable for manufacturing use

suitability

-

suitability

-

suitability

-

solubility

H2O: 10 mg/mL, clear, colorless

solubility

H2O: soluble

solubility

H2O: 0.1 M at 20 °C, clear, colorless

solubility

water: 1 mg/mL, DMF: 10 mg/mL, ethanol: 5 mg/mL

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

400

Quality Level

300

Quality Level

200

Quality Level

200

Amino Acid Sequence

Glu-Cys-Gly, Glu-Cys-Gly [Disulfide bridge: 2a-2b]

General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000490312
0000490311
0000490311
0000490312
0000444997

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Kun-Peng Wang et al.
Molecular medicine reports, 9(5), 1813-1819 (2014-03-08)
Schisandra chinensis is a well-known traditional medicinal herb. Acetaminophen is a commonly used over-the-counter analgesic and overdose of acetaminophen was the most frequent cause of acute liver failure. However, no studies have demonstrated the role of Schisandra chinensis in acetaminophen-induced
Fabio Di Domenico et al.
Expert review of neurotherapeutics, 15(1), 19-40 (2014-09-23)
Alzheimer's disease (AD), characterized by progressive loss of memory, language, reasoning and other cognitive functions, including dementia, is characterized pathologically by the presence of senile plaques, neurofibrillary tangles and synapse loss. Increased oxidative/nitrosative stress, decreased antioxidants, mitochondrial damage and other
Benoît Tessoulin et al.
Blood, 124(10), 1626-1636 (2014-07-10)
The aim of this study was to assess the efficiency of p53 reactivation and induction of massive apoptosis (PRIMA-1(Met)) in inducing myeloma cell death, using 27 human myeloma cell lines (HMCLs) and 23 primary samples. Measuring the lethal dose (LD50)
Vladimir L Kolossov et al.
Experimental biology and medicine (Maywood, N.J.), 239(4), 394-403 (2014-03-04)
The glutathione couple GSH/GSSG is the most abundant cellular redox buffer and is not at equilibrium among intracellular compartments. Perturbation of glutathione poise has been associated with tumorigenesis; however, due to analytical limitations, the underlying mechanisms behind this relationship are
Changchun Cai et al.
Hepatology (Baltimore, Md.), 60(3), 990-1002 (2014-05-07)
Acetaminophen (APAP) toxicity is the most common cause of acute liver failure in industrialized countries. Understanding the mechanisms of APAP-induced liver injury as well as other forms of sterile liver injury is critical to improve the care of patients. Recent
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