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Merck

P1629

TWEEN® 60

nonionic detergent

Synonym(s):

Polyethylene glycol sorbitan monostearate, Polyoxyethylene sorbitan monostearate

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100 ML

€55.00

500 ML

€71.90

1 GAL

€239.00

€55.00


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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12161900
NACRES:
NA.25

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Quality Level

mol wt

estimated mol wt 1309

composition

stearic acid, 40-60%
total stearic and palmitic acid, ≥90%

technique(s)

DNA extraction: suitable
RNA extraction: suitable
cell culture | mammalian: suitable
protein purification: suitable

CMC

27 mg/L

density

1.044 g/mL at 25 °C (lit.)

HLB

14.9

SMILES string

O1C(C(C(C1)OCCO)OCCO)C(OCCO)COCCOC(=O)CCCCCCCCCCC

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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1 of 4

This Item
8.221868.170761547947
technique(s)

DNA extraction: suitable, cell culture | mammalian: suitable, RNA extraction: suitable, protein purification: suitable

technique(s)

-

technique(s)

API processing | nano-milling: suitable

technique(s)

-

density

1.044 g/mL at 25 °C (lit.)

density

1.1 g/cm3 at 20 °C

density

1.1 g/cm3 at 20 °C

density

-

CMC

27 mg/L

CMC

-

CMC

-

CMC

-

mol wt

estimated mol wt 1309

mol wt

-

mol wt

-

mol wt

-

Quality Level

200

Quality Level

200

Quality Level

500

Quality Level

-

HLB

14.9

HLB

-

HLB

-

HLB

-

General description

TWEEN 60 is a niosome. [1]

Application

Polyethylene glycol sorbitan monostearate, or TWEEN 60, has been used in a study to assess encapsulation of functional lipophilic components in surfactant-based colloidal delivery systems. [2] It has also been used in a study to investigate doxorubicin loaded magneto-niosomes for targeted drug delivery. [3]

Legal Information

TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Khalid Ziani et al.
Food chemistry, 134(2), 1106-1112 (2012-10-31)
The fabrication and stability of surfactant-based colloidal delivery systems (microemulsions and emulsions) suitable for encapsulation of lipophilic active agents (vitamins and flavours) was investigated. An emulsion titration method was used to study the influence of surfactant type (Tween 20, 60
Physicochemical properties and skin permeation of [TM="Span"] 60/Tween 60 niosomes of ellagic acid
Burapacheep, V., et al.
International Journal of Pharmaceutics, 432, 9-9 (2012)
Lorena Tavano et al.
Colloids and surfaces. B, Biointerfaces, 102, 803-807 (2012-10-31)
In chemotherapy the magnetic drug targeting to a specific organ or tissue is proposed on the assumption that magnetic fields are harmless to biological systems. In this light we have vehiculated doxorubicin as model drug by novel magneto-niosomes in order
Ray F David et al.
Fungal genetics and biology : FG & B, 96, 25-32 (2016-10-22)
The plant pathogenic ascomycete Fusarium graminearum produces perithecia on corn and small grain residues. These perithecia forcibly discharge ascospores into the atmosphere. Little is known about the relationship among the strength of the perithecial wall, the age of the perithecium
Rafaela C Sartore et al.
PloS one, 6(6), e20667-e20667 (2011-06-16)
The existence of loss and gain of chromosomes, known as aneuploidy, has been previously described within the central nervous system. During development, at least one-third of neural progenitor cells (NPCs) are aneuploid. Notably, aneuploid NPCs may survive and functionally integrate

Articles

DISCOVER Bioactive Small Molecules for Neuroscience

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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