The molarity of this product (Sodium hydroxide solution) is 1.0 N. For sodium hydroxide, a 1.0 N solution is equivalent to a 1.0 M solution because NaOH is a monoprotic base, providing 1 equivalent per mole.
S2770
Sodium hydroxide solution
1.0 N, BioReagent, suitable for cell culture
Synonym(s):
Caustic Soda, Lye, NaOH, Soda
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About This Item
Linear Formula:
NaOH
CAS Number:
Molecular Weight:
40.00
MDL number:
UNSPSC Code:
12352316
PubChem Substance ID:
NACRES:
NA.71
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vapor pressure
3 mmHg ( 37 °C)
sterility
sterile-filtered
product line
BioReagent
form
solution
concentration
1.0 N
technique(s)
cell culture | mammalian: suitable
SMILES string
[OH-].[Na+]
InChI
1S/Na.H2O/h;1H2/q+1;/p-1
InChI key
HEMHJVSKTPXQMS-UHFFFAOYSA-M
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This Item | 72068 | 72064 | 79724 |
|---|---|---|---|
| concentration 1.0 N | concentration 10 M in H2O, 9500-10500 mmol/L (titration, acidimetric) | concentration 49-51% in water | concentration 0.9-1.1 M |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| form solution | form liquid | form liquid | form liquid |
| vapor pressure 3 mmHg ( 37 °C) | vapor pressure 3 mmHg ( 37 °C) | vapor pressure 3 mmHg ( 37 °C) | vapor pressure 3 mmHg ( 37 °C) |
| sterility sterile-filtered | sterility - | sterility - | sterility - |
| product line BioReagent | product line BioUltra | product line - | product line - |
General description
Sodium hydroxide is a strong alkali. Its reaction with acid yields salt and water. Sodium hydroxide solution has many industrial applications including dyes and drugs. It has the ability to disintegrate lignin and hence is used in paper manufacturing. Sodium hydroxide has high melting of about 318°C.[1]
Application
Sodium hydroxide solution has been used:
- to neutralize collagen type I solution phosphate-buffered saline for its use in 3D cell culture technique[2]
- to dissolve phosphate chains in phosphate glass for optical characterisation[3]
- as a component of transfer medium used for cell culture[4]
- as a general titration base for cell culture applications.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
Storage Class Code
8B - Non-combustible corrosive hazardous materials
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Sodium, 21-21 (2002)
Matrix dimensions, stiffness, and structural properties modulate spontaneous chondrogenic commitment of mouse embryonic fibroblasts
Fernandez MT
Tissue Engineering: Part A, 20(7-8), 1145-1155 (2013)
Optical characterisation of hydroxide catalysed bonds applied to phosphate glass
Optifab, 10448, 1044825-1044825 (2017)
Isolation and culture of human endometrial epithelial cells and stromal fibroblasts
Chen JC and Roan NR
Bio-protocol, 5(20) (2015)
Konstantinos A Polyzos et al.
Cardiovascular research, 106(2), 295-302 (2015-03-10)
Atherosclerosis is a chronic inflammatory disease that is initiated by the retention and accumulation of low-density lipoprotein in the artery, leading to maladaptive response of cells from the immune system and vessel wall. Strong evidence implicates indoleamine 2,3-dioxygenase (IDO), the
Protocols
3-D Culture Matrix™ Collagen I facilitates cellular growth and differentiation in vitro, offering versatile applications in biomedical research.
Preparation from Packaged Powder, Preparation from Basal Salt Solutions, Banana Powder Preparation and Use, Coconut Water Preparation and Use
Related Content
Product Information Sheet
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What is the molarity of this product?
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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What is the stability period for this product (S-2770), as there is no expiration date on the bottle?
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This item is not assigned an expiration or retest date and is robust in nature, being extremely stable in the original, unopened container. Products that are not assigned an expiration or retest date are covered by a warranty period of 1 year from the date of product shipment.??? Please see the link below to review the full Product Dating Information statement:
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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Is this product Molecular Biology Grade?
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This product has been tested for use in Cell Culture applications and would not be considered a Molecular Biology grade item. Product 72068, Sodium Hydroxide BioUltra for Molecular Biology may be of interest. This product is only available at a 10M concentration. Please see the link below to review this product option:
https://www.sigmaaldrich.com/product/sigma/72068Helpful?
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