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S7152

Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe

≥97% (HPLC), suitable for ligand binding assays and ELISA

Synonym(s):

SFLLRNPNDKYEPF, TRAP, Thrombin Receptor Activator Peptide

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250 μG

€194.25

1 MG

€727.60

€194.25

List Price€259.00Save 25%
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About This Item

Empirical Formula (Hill Notation):
C81H118N20O23
CAS Number:
137339-65-2
Molecular Weight:
1739.92
UNSPSC Code:
12352209
PubChem Substance ID:
24899735
NACRES:
NA.26
MDL number:
MFCD00133815

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Product Name

Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe, ≥97% (HPLC)

SMILES string

CC(C)CC(NC(=O)C(CC(C)C)NC(=O)C(Cc1ccccc1)NC(=O)C(N)CO)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(N)=O)C(=O)N2CCCC2C(=O)NC(CC(N)=O)C(=O)NC(CC(O)=O)C(=O)NC(CCCCN)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(CCC(O)=O)C(=O)N4CCCC4C(=O)NC(Cc5ccccc5)C(O)=O

InChI

1S/C81H118N20O23/c1-43(2)34-53(93-71(114)54(35-44(3)4)94-73(116)55(92-67(110)49(83)42-102)36-45-16-7-5-8-17-45)70(113)90-51(21-13-31-88-81(86)87)69(112)98-59(40-64(85)105)79(122)101-33-15-22-61(101)76(119)97-57(39-63(84)104)74(117)96-58(41-66(108)109)75(118)89-50(20-11-12-30-82)68(111)95-56(37-47-24-26-48(103)27-25-47)72(115)91-52(28-29-65(106)107)78(121)100-32-14-23-62(100)77(120)99-60(80(123)124)38-46-18-9-6-10-19-46/h5-10,16-19,24-27,43-44,49-62,102-103H,11-15,20-23,28-42,82-83H2,1-4H3,(H2,84,104)(H2,85,105)(H,89,118)(H,90,113)(H,91,115)(H,92,110)(H,93,114)(H,94,116)(H,95,111)(H,96,117)(H,97,119)(H,98,112)(H,99,120)(H,106,107)(H,108,109)(H,123,124)(H4,86,87,88)

InChI key

OXHYRVSBKWIFES-UHFFFAOYSA-N

assay

≥97% (HPLC)

form

powder

composition

Peptide content, ~70%

technique(s)

ELISA: suitable
ligand binding assay: suitable

color

white

storage temp.

−20°C

Quality Level

200

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Show Differences

1 of 4

This Item
C1141S1820A9519
Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe ≥97% (HPLC)

Sigma-Aldrich

S7152

Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe

Z-Phe-Leu

Sigma-Aldrich

C1141

Z-Phe-Leu

Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt ≥98% (HPLC), lyophilized powder

Sigma-Aldrich

S1820

Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt

N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate ≥98% (TLC)

Sigma-Aldrich

A9519

N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate

form

powder

form

powder

form

lyophilized powder

form

powder

technique(s)

ELISA: suitable, ligand binding assay: suitable

technique(s)

ligand binding assay: suitable

technique(s)

-

technique(s)

ligand binding assay: suitable

assay

≥97% (HPLC)

assay

≥98% (TLC)

assay

≥98% (HPLC)

assay

≥98% (TLC)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

color

white

color

white

color

white

color

white

Biochem/physiol Actions

Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe has contractile effects on vascular and gastric smooth muscle. It stimulates the hydrolysis of phosphoinositides.[1]
Thrombin receptor activator

Other Notes

Lyophilized from 0.1% TFA in H2O

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000360736
0000284038
0000284038
0000284037
0000284037

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Experimental animals, 68(3), 371-380 (2019-04-05)
Ketogenic diet (KD) has been used in epilepsy for decades, but previous studies found it may cause severe bone loss. Every-other-day ketogenic diet (EODKD), the combination of KD with intermittent fasting, showed better potential for seizure control recently, while its
Relaxant and contractile responses of porcine pulmonary arteries to a thrombin receptor activating peptide (TRAP)
Glusa E and Manfred P
Naunyn-Schmiedeberg'S Archives of Pharmacology, 394(4), 431-443 (1994)
Nobumasa Soda et al.
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Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 34(8), 1473-1486 (2019-06-13)
The absence of functional dystrophin with mutations of the dystrophin-encoding gene in Duchenne muscular dystrophy (DMD) results in muscle inflammation and degeneration, as well as bone fragility. Long-term glucocorticoid therapy delays the muscular disease progression but suppresses growth hormone secretion
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