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Merck

CDK7

cyclin-dependent kinase 7

別名:
CAK1, CDKN7, HCAK, MO15, STK1, p39MO15
Species:
Human CDK7 (1022), Mouse Cdk7 (12572), Rat Cdk7 (171150), domestic guinea pig Cdk7 (100725955), naked mole-rat Cdk7 (101702664), sheep CDK7 (101119934), Horse CDK7 (100049964), Zebrafish cdk7 (405897), dog CDK7 (608441), domestic cat CDK7 (101086781) ...詳細
UniProtKB ID:
P50613, Q9BS60, Q9UE19
遺伝子ID:
  • Human(1022) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
  • Mouse(12572) cyclin-dependent kinase 7
  • Rat(171150) cyclin-dependent kinase 7
  • domestic guinea pig(100725955) cyclin-dependent kinase 7
  • naked mole-rat(101702664) cyclin-dependent kinase 7
  • sheep(101119934) cyclin-dependent kinase 7
  • Horse(100049964) cyclin-dependent kinase 7
  • Zebrafish(405897) cyclin-dependent kinase 7
  • dog(608441) cyclin-dependent kinase 7
  • domestic cat(101086781) cyclin-dependent kinase 7
  • chicken(771294) cyclin-dependent kinase 7
  • cow(515462) cyclin-dependent kinase 7
  • fruit fly(31441) Cyclin-dependent kinase 7

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Antibodies

製品番号
詳細
交差性
アプリケーション
ABE1317
Anti-phospho Cyclin-dependent kinase 7 (Thr170) Antibody, from rabbit, purified by affinity chromatography,
交差性
human, mouse, rat
アプリケーション
ChIP
western blot
HPA007932
抗CDK7抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
C7089
Monoclonal Anti-Cdk7/CAK antibody produced in mouse, clone MO-1.1, ascites fluid,
交差性
human
アプリケーション
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
HPA008453
Anti-CDK7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
western blot
WH0001022M1
Monoclonal Anti-CDK7 antibody produced in mouse, clone 1G5, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA

Small Molecule - Inhibitor

製品番号
詳細
Species
F3055
フラボピリドール 塩酸塩 水和物, ≥98% (HPLC), powder,
Species
human
R7772
ロスコビチン, ≥98% (TLC),
Species
human, mouse, rat
O0886
オロモウシン, ≥98% (HPLC),
Species
human, rat

Proteins

製品番号
詳細
Species
14-476-M
Cdk7/Cyclin H/MAT1 (CAK complex) Protein, active, 10 µg, Active complex of recombinant full length human Cdk7, containing a C-terminal His6-tag, recombinant full-length human Cyclin H untagged & recombinant full-length human MAT1 containing an N-terminal GST-tag, for use in Kinase Assays.,
Species
human

esiRNA

製品番号
詳細
Species
EMU067531
MISSION® esiRNA, targeting mouse Cdk7,
Species
mouse
EHU108561
MISSION® esiRNA, targeting human CDK7,
Species
human

Small Molecule - Substrate

製品番号
詳細
Species
12-526
Cdk7/9tide, ,
Species
human