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Merck

485896

L-Asparagine-(amide-15N) monohydrate

98 atom % 15N

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250 MG

₩1,032,255

₩1,032,255


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About This Item

Linear Formula:
H215NCOCH2CH(NH2)CO2H · H2O
CAS Number:
Molecular Weight:
151.13
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.12

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Product Name

L-Asparagine-(amide-15N) monohydrate, 98 atom % 15N

SMILES string

O.N[C@@H](CC([15NH2])=O)C(O)=O

InChI

1S/C4H8N2O3.H2O/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H2,6,7)(H,8,9);1H2/t2-;/m0./s1/i6+1;

InChI key

RBMGJIZCEWRQES-UEFLAVRISA-N

isotopic purity

98 atom % 15N

form

solid

optical activity

[α]20/D +31.5°, c = 1 in 1 M HCl

mp

233-235 °C (lit.)

mass shift

M+1

Quality Level

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This Item
489964579866641960
isotopic purity

98 atom % 15N

isotopic purity

98 atom % 15N

isotopic purity

99 atom % 13C

isotopic purity

98 atom % 15N

mass shift

M+1

mass shift

M+1

mass shift

M+1

mass shift

M+2

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

solid

form

solid

form

solid

form

solid

mp

233-235 °C (lit.)

mp

233-235 °C (lit.)

mp

233-235 °C (lit.)

mp

232 °C (dec.) (lit.)

optical activity

[α]20/D +31.5°, c = 1 in 1 M HCl

optical activity

[α]20/D +31.5°, c = 1 in 1 M HCl

optical activity

[α]25/D +31.5°, c = 1 in 1 M HCl

optical activity

-

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Jun Wu et al.
Nature cell biology, 23(1), 75-86 (2021-01-10)
Nutrient availability is central for T-cell functions and immune responses. Here we report that CD8+ T-cell activation and anti-tumour responses are strongly potentiated by the non-essential amino acid Asn. Increased Asn levels enhance CD8+ T-cell activation and effector functions against
Longfei Deng et al.
Nature communications, 11(1), 1755-1755 (2020-04-11)
Asparagine synthetase (ASNS) catalyses the ATP-dependent conversion of aspartate to asparagine. However, both the regulation and biological functions of asparagine in tumour cells remain largely unknown. Here, we report that p53 suppresses asparagine synthesis through the transcriptional downregulation of ASNS

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