Merck

Affinity Chromatography Resins

A laboratory setting showcasing the tools and chemicals used in affinity chromatography. In the foreground, three bottles labeled with hazard symbols indicate the presence of flammable and corrosive substances, essential for selective biochemical interactions and purification processes. In the background, a scientist in a lab coat is engaged with complex equipment, likely related to large-scale manufacturing and process development in affinity chromatography.

Affinity chromatography separates complex mixtures through highly selective biochemical interactions. This widely used purification technology efficiently separates a target molecule from impurities. Our range of affinity resins are designed for high throughput and cost-effective purification, from process development through large-scale manufacturing.



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Protein A Affinity Resins

Eshmuno® A is a high-capacity resin for the purification of Fc-containing proteins, such as monoclonal antibodies (mAbs). This resin can be sanitized under acid and alkaline conditions.

Affinity Resins for Plasma Purification

Eshmuno® P anti-A and anti-B resins effectively remove anti-A and anti-B isoagglutinin antibodies in plasma-derived Immunoglobulin (Ig) processes, which has been associated with increased patient risk for hemolysis.

Affinity Resins for Protein Purification

Fractogel® Metal Chelate resin offers efficient and cost-effective separation of proteins and peptides, especially proteins with exposed histidine, cysteine, and tryptophan residues, including histidine-tagged proteins.

Support for qualification, risk assessment, and process optimization

Complementing our product portfolio, the Emprove® Program provides three types of dossiers to support different stages of development and manufacturing operations such as qualification, risk assessment, and process optimization. The dossiers consolidate comprehensive product-specific testing data, quality statements, and regulatory information in a readily available format to simplify your compliance needs.




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