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Merck

40407

1,7-Dimethyluric acid

≥97.0% (HPLC)

동의어(들):

1,7-Dimethyl-2,6,8-trihydroxypurine

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크기 선택

250 MG

₩263,900

₩263,900

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C7H8N4O3
CAS 번호:
33868-03-0
Molecular Weight:
196.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
57649989
EC Number:
251-706-2
Beilstein/REAXYS Number:
219682
MDL number:
MFCD00005713
Assay:
≥97.0% (HPLC)

주요 문서

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도움 문의

InChI key

NOFNCLGCUJJPKU-UHFFFAOYSA-N

InChI

1S/C7H8N4O3/c1-10-3-4(8-6(10)13)9-7(14)11(2)5(3)12/h1-2H3,(H,8,13)(H,9,14)

SMILES string

CN1C(=O)NC2=C(N(C)C(=O)N2)C1=O

assay

≥97.0% (HPLC)

Quality Level

100

관련 카테고리

General description

1,7-Dimethyluric acid is an important metabolite of caffeine.[1] Electrochemical oxidation of 1,7-dimethyluric acid was studied over a wide pH range of 2.2-10.3 at solid electrodes.[2]

Application

1,7-Dimethyluric acid is the suitable reagent used for the simultaneous determination of plasma levels of theophylline and its metabolites without interference from caffeine or caffeine metabolites by HPLC.[1]

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
BCCM8942
BCCH7932
BCCF3606
BCBW5333
BCBQ3254V

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COA 검색

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문서 라이브러리 방문

Electrochemical and peroxidase catalysed oxidation of 1, 7-dimethyluric acid and effect of methyl groups on the oxidation mechanism.
Goyal RN, et al.
J. Chem. Soc. Perkin Trans. II, 6, 1153-1159 (1996)
J Kizu et al.
Biomedical chromatography : BMC, 13(1), 15-23 (1999-04-07)
A high performance liquid chromatography (HPLC) method has been developed for the simultaneous determination of plasma levels of theophylline and its metabolites without interference from caffeine or caffeine metabolites. The method is simple and of practical use because it is
M Vincent-Viry et al.
Genetic epidemiology, 11(2), 115-129 (1994-01-01)
Human acetylation phenotypes were determined with caffeine (137X) as the test substance, improved by measuring urinary caffeine metabolites with a previously described HPLC method. Caffeine, 5-acetylamino-6-formylamino-3-methyluracil (AFMU), 1-methylxanthine (IX), 1-methyluric acid (IU), 1,7-dimethylxanthine (17X), and 1,7-dimethyluric acid (17U) were quantified.
Frank Haberman et al.
Neuromolecular medicine, 9(4), 315-323 (2007-11-14)
Uric acid is a major antioxidant in the blood of humans that can protect cultured neurons against oxidative and metabolic insults. However, uric acid has a very low solubility which compromises its potential clinical use for neurodegenerative disorders. Here we
E Asprodini et al.
The Journal of pharmacology and experimental therapeutics, 368(2), 262-271 (2018-12-29)
The purpose of the study was to determine whether the in vivo activities of drug-metabolizing enzymes CYP1A2 and CYP2A6, xanthine oxidase (XO), and N-acetyltransferase-2 (NAT2) vary across the menstrual cycle. Forty-two healthy women were studied at early follicular phase (EFP:
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