8.52182
Fmoc-Tyr(tBu)-Thr(psiMe,Mepro)-OH
Novabiochem®
동의어(들):
Fmoc-Tyr(tBu)-Thr(psiMe,Mepro)-OH
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
| 사이즈/SKU | 재고 정보 | 가격 (VAT 별도) |
|---|---|---|
5 g | 구입 가능 여부는 고객센터에 문의하십시오. | ₩521,710 |
구입 가능 여부는 고객센터에 문의하십시오. | ₩2,277,762 | |
구입 가능 여부는 고객센터에 문의하십시오. | ₩6,102,282 |
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C35H40N2O7
CAS 번호:
Molecular Weight:
600.70
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22
Quality Segment
product line
Novabiochem®
assay
≥97% (TLC), ≥97.0% (HPLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
hydroxyl
storage temp.
2-8°C
SMILES string
N5([C@@H]([C@H](OC5(C)C)C)C(=O)O)C(=O)[C@@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)Cc1ccc(cc1)OC(C)(C)C
InChI
1S/C35H40N2O7/c1-21-30(32(39)40)37(35(5,6)43-21)31(38)29(19-22-15-17-23(18-16-22)44-34(2,3)4)36-33(41)42-20-28-26-13-9-7-11-24(26)25-12-8-10-14-27(25)28/h7-18,21,28-30H,19-20H2,1-6H3,(H,36,41)(H,39,40)/t21-,29+,30+/m1/s1
InChI key
JYSMURJYNLWZNY-RIGQTMPJSA-N
General description
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Tyr-Thr dipeptide motif. It consists of a dipeptide in which the threonine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The threonine residue is regenerated during the normal TFA-mediated cleavage reaction.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aggregation in Fmoc SPPS
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aggregation in Fmoc SPPS
Analysis Note
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): -32.0 - -26.0 °
Purity (TLC(157A)): ≥ 97 %
Purity (TLC(CMA2)): ≥ 97 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Single impurities (HPLC, area%): ≤ 1.00 % (a/a)
Ethyl acetate (HS-GC): ≤ 2.0 %
Acetate (IC): ≤ 0.1 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): -32.0 - -26.0 °
Purity (TLC(157A)): ≥ 97 %
Purity (TLC(CMA2)): ≥ 97 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Single impurities (HPLC, area%): ≤ 1.00 % (a/a)
Ethyl acetate (HS-GC): ≤ 2.0 %
Acetate (IC): ≤ 0.1 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
Other Notes
Replaces: 05-20-1007
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
저장 등급
11 - Combustible Solids
무슨 일이 일어나고 있는 걸까?
WGK 2
인화점 (F)
Not applicable
인화점 (°C)
Not applicable