SAB4200375
Anti-UGGT1 (mouse) antibody produced in rabbit
~1.0 mg/mL, affinity isolated antibody
동의어(들):
Anti-HUGT1, Anti-UDP-glucose glycoprotein glucosyltransferase 1, Anti-UGCGL1, Anti-UGT1
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제품정보 (DICE 배송 시 비용 별도)
NACRES:
NA.41
UNSPSC Code:
12352203
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~170 kDa
species reactivity
rat, mouse
concentration
~1.0 mg/mL
technique(s)
western blot: 2.5-5.0 μg/mL using whole extracts of mouse RAG or rat NRK cells.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... Uggt1(320011)
rat ... Uggt1(171129)
General description
Uridine diphosphate (UDP)-glucose:glycoprotein glucosyltransferase 1 (UGGT1) is a large soluble protein of the endoplasmic reticulum (ER). It contains a N-terminal folding sensor domain and a C-terminal catalytic domain that transfers glucose residues. It is a member of the glycosyltransferase family 24.
Immunogen
synthetic peptide corresponding to the C-terminal region of mouse UGGT1, conjugated to KLH. The corresponding sequence differs by one amino acid in rat.
Application
Anti-UGGT1 (mouse) antibody produced in rabbit may be used in immunoblotting.
Biochem/physiol Actions
Anti-UGGT1 (mouse) recognizes mouse and rat UGGT1.
Uridine diphosphate (UDP)-glucose:glycoprotein glucosyltransferase 1 (UGGT1) that selectively re-glucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the endoplasmic reticulum (ER). It re-glucosylates incompletely folded glycoproteins to monoglucosylated intermediates. Re-glucosylated proteins are recognized by ER-resident carbohydrate-binding molecular chaperons, calnexin or calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Preparation Note
For continuous use, store at 2-8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.
Disclaimer
Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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저장 등급
10 - Combustible liquids
인화점 (F)
Not applicable
인화점 (°C)
Not applicable