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Merck

128708

trans-Ferulic acid

99%

Synonym(s):

trans-4-Hydroxy-3-methoxycinnamic acid, Ferulic acid

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About This Item

Linear Formula:
HOC6H3(OCH3)CH=CHCO2H
CAS Number:
537-98-4
Molecular Weight:
194.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24847872
EC Number:
208-679-7
Beilstein/REAXYS Number:
1570363
MDL number:
MFCD00004400

Key Documents

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Product Name

trans-Ferulic acid, 99%

InChI key

KSEBMYQBYZTDHS-HWKANZROSA-N

InChI

1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+

SMILES string

OC(/C=C/C1=CC(OC)=C(O)C=C1)=O

assay

99%

form

powder
powder and chunks

mp

168-172 °C (lit.)

functional group

carboxylic acid

Quality Level

200

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1 of 4

This Item
W51830152229Y0001013
trans-Ferulic acid 99%

Sigma-Aldrich

128708

trans-Ferulic acid

trans-Ferulic acid ≥99%

Sigma-Aldrich

W518301

trans-Ferulic acid

trans-Ferulic acid certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

52229

trans-Ferulic acid

Ferulic acid European Pharmacopoeia (EP) Reference Standard

Y0001013

Ferulic acid

assay

99%

assay

≥99%

assay

-

assay

-

Quality Level

200

Quality Level

400

Quality Level

300

Quality Level

-

form

powder, powder and chunks

form

powder

form

-

form

-

mp

168-172 °C (lit.)

mp

168-172 °C (lit.)

mp

168-172 °C (lit.)

mp

168-172 °C (lit.)

functional group

carboxylic acid

functional group

-

functional group

-

functional group

-

Application

trans-Ferulic acid was used for esterification of methacrylated dextran[1]. It was also used to study the effect of oral administration of trans-ferulic acid to c57BL mice on ethanol-induced liver injury[2]. Furthermore, it has been used in the synthesis of new biocompatible antioxidant polymers linking trans-ferulic acid[3].

Biochem/physiol Actions

Hydroxycinnamic acid found in plant-based foods. Antioxidant.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF7378V
0000493347
0000493347
WXBF5113V
WXBF2985V

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Roberta Cassano et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 72(1), 232-238 (2008-11-04)
Long-term exposure of the skin to UV light causes degenerative effects, which can be minimized by using antioxidant formulations. The major challenge in this regard is that a significant amount of antioxidant should reach at the site for effective photoprotection.
Chatchawan Chotimarkorn et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 15(11), 951-958 (2008-04-22)
The effects of the oral administration of trans-ferulic acid and gamma-oryzanol (mixture of steryl ferulates) with ethanol (5.0 g per kg) for 30 days to c57BL mice on ethanol-induced liver injury were investigated. Preventions of ethanol-induced liver injury by trans-ferulic
Sonia Trombino et al.
Journal of agricultural and food chemistry, 52(8), 2411-2420 (2004-04-15)
Although an antioxidant mechanism has been involved in the beneficial effects of ferulic acid in human diseases, there are few reports on the antioxidant properties of this compound in isolated membranes and intact cells. Here, we evaluated the ability of
Nickolas A Anderson et al.
The Plant cell, 27(8), 2195-2209 (2015-08-13)
Modifying lignin composition and structure is a key strategy to increase plant cell wall digestibility for biofuel production. Disruption of the genes encoding both cinnamyl alcohol dehydrogenases (CADs), including CADC and CADD, in Arabidopsis thaliana results in the atypical incorporation
J P Rosazza et al.
Journal of industrial microbiology, 15(6), 457-471 (1995-12-01)
In this review we examine the fascinating array of microbial and enzymatic transformations of ferulic acid. Ferulic acid is an extremely abundant, preformed phenolic aromatic chemical found widely in nature. Ferulic acid is viewed as a commodity scale, renewable chemical
View All Related Papers

Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

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