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Merck

35032

Fenbendazole

VETRANAL®, analytical standard

Synonym(s):

Methyl 5-(phenylthio)-2-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):
C15H13N3O2S
CAS Number:
Molecular Weight:
299.35
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
256-145-7
Beilstein/REAXYS Number:
759077
MDL number:

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Product Name

Fenbendazole, VETRANAL®, analytical standard

InChI key

HDDSHPAODJUKPD-UHFFFAOYSA-N

InChI

1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

SMILES string

COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

Quality Level

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This Item
PHR1832F5396F0040000
application(s)

clinical testing

application(s)

pharmaceutical

application(s)

-

application(s)

pharmaceutical (small molecule)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

Quality Level

100

Quality Level

300

Quality Level

200

Quality Level

-

grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

pharmaceutical primary standard

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

product line

VETRANAL®

product line

-

product line

-

product line

-

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Chemical structure: benzimidazole
Fenbendazole is a thio substituted benzimidazole, which belongs to the group of anthelmintics.[1] It can be widely used in veterinary medicine particularly, in the treatment of helminth infections.[2]

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Product No.
Description
Pricing

pictograms

Health hazardEnvironment

signalword

Warning

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2

target_organs

Liver,lymph node,Stomach,Nervous system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)


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Determination of fenbendazole and oxfendazole in liver and muscle using liquid chromatography?mass spectrometry
Blanchflower J.W, et al.
Analyst, 119, 1325-1328 (1994)
Interaction between fenbendazole and piperonyl butoxide: pharmacokinetic and pharmacodynamic implications
Benchaoui.A.H and Mckellar.A.Q
The Journal of Pharmacy and Pharmacology, 48, 753-759 (1996)
A C Clark et al.
The Journal of small animal practice, 54(2), 99-103 (2012-11-14)
A 4-year-old, spayed-female great Dane was referred for surgical treatment of a suspected meningioma, diagnosed on magnetic resonance imaging 10 days prior to presentation. The suspected meningioma was removed via image-guided stereotactic craniotomy. Histopathological diagnosis was severe, locally extensive, chronic meningoencephalitis
Aileen Adam et al.
Veterinary parasitology, 177(3-4), 383-386 (2011-01-18)
On red grouse estates in the UK the nematode parasite Trichostrongylus tenuis is often controlled by application of grit medicated with the anthelmintic fenbendazole (FBZ). To date, assessment of the efficacy has been inhibited by the inability to quantify uptake
Moreno Rossi et al.
Journal of feline medicine and surgery, 13(10), 793-795 (2011-08-13)
An 8-month-old owned European cat showing abdominal pain, fever, distended painful bladder and urinary blockage was presented. Intravenous fluids were immediately administered and, after sedation, a urinary catheter was applied. Blood and urine analysis revealed cystitis and a moderate-to-severe degree

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