L5750

Sodium dodecyl sulfate

92.5-100.5% based on total alkyl sulfate content basis

• Synonym(s): Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Linear Formula: CH₃(CH₂)₁₁OSO₃Na
• CAS Number: 151-21-3
• Molecular Weight: 288.38
• NACRES: NA.21
• PubChem Substance ID: 24896412
• eCl@ss: 39093306
• UNSPSC Code: 12161900
• EC Number: 205-788-1
• MDL number: MFCD00036175
• Beilstein/REAXYS Number: 3599286

Properties

• Product Name: Sodium dodecyl sulfate, 92.5-100.5% based on total alkyl sulfate content basis
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• SMILES string: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI key: DBMJMQXJHONAFJ-UHFFFAOYSA-M
• description: anionic
• assay: 92.5-100.5% based on total alkyl sulfate content basis
• mol wt: 288.38 g/mol
• Quality Level: 200
• greener alternative product characteristics: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• aggregation number: 62
• technique(s): : suitable using [cell culture | mammalian: suitable]
• CMC: 7-10 mM (20-25°C)
• mp: 204-207 °C (lit.)
• transition temp: cloud point >100 °C
• solubility: water: soluble
• HLB: 40
• application(s): (Western Blot)
• greener alternative category: Aligned

Description

Analysis Note

Actual composition given on label

Predominantly (approx. 70%) C₁₂; lauryl sulfate, sodium salt; balance consists of higher homologs.

Application

Anionic detergent

Sodium dodecyl sulfate has been used:

• to dissolve insoluble purple formazan in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay
• to perform SDS–PAGE of yeast tubulin
• as an additive in linolenic acid solution to assess the total antioxidative activity (TAA) of the bacteria using the linolenic acid test (LA-test)

Biochem/physiol Actions

Sodium dodecyl sulfate (SDS)/lauryl sulfate, an ionic detergent has the ability to distract biological membranes. It can block RNase and deoxyribonuclease (DNase) activity. SDS is one of the main constituents of several reagents, that are used to purify nucleic acids. It is also considered as a permeability enhancer in oral formulations.

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is used as a surfactant to enhance catalysis.  Click here for more information.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H315,H318,H412
• pcodes: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: 338.0 °F
• flash_point_c: 170 °C
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges