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Flavin-Containing Monooxygenase-1, Microsomes human

Name: Flavin-Containing Monooxygenase-1, Microsomes human
Brand: SIGMA

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution

Synonym(s):

FMO-1

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About This Item

EC Number:

1.14.13.8 (BRENDA, IUBMB)

NACRES:

NA.54

UNSPSC Code:

12352204

Specific activity:

See COA for Value

Recombinant:

expressed in baculovirus infected insect cells

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Properties

recombinant

expressed in baculovirus infected insect cells

Quality Segment

200

form

buffered aqueous solution

specific activity

See COA for Value

mol wt

55-60 kDa

packaging

vial of 2.5 mg

UniProt accession no.

Q01740

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... FMO1(2326)

Description

Biochem/physiol Actions

The FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens which contain a nucleophilic nitrogen, sulfur, selenium, or phosphorus-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes.

Physical form

Solution in 100 mM potassium phosphate buffer, pH 7.4.

Other Notes

One unit will catalyze the production of 1.0 picomole of methyl p-tolylsulfoxide from methyl p-tolyl sulfide per minute at pH 9.5 at 37 deg C.

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This Item	HPA023680	F5053	F5178
Sigma-Aldrich F4928 Flavin-Containing Monooxygenase-1, Microsomes human	Sigma-Aldrich HPA023680 Anti-FMO1 antibody produced in rabbit	Sigma-Aldrich F5053 Flavin-Containing Monooxygenase-3, Microsomes human	Sigma-Aldrich F5178 Flavin-Containing Monooxygenase-5, Microsomes human
description recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	description recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution	description recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
specific activity See COA for Value	specific activity -	specific activity -	specific activity ≥700 units/mg protein
Gene Information human ... FMO1(2326)	Gene Information human ... FMO1(2326)	Gene Information human ... FMO3(2328)	Gene Information human ... FMO5(2330)
recombinant expressed in baculovirus infected insect cells	recombinant -	recombinant expressed in baculovirus infected insect cells	recombinant expressed in baculovirus infected insect cells
form buffered aqueous solution	form buffered aqueous glycerol solution	form buffered aqueous solution	form buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
storage temp. −70°C	storage temp. −20°C	storage temp. −70°C	storage temp. −70°C
UniProt accession no. Q01740	UniProt accession no. Q01740	UniProt accession no. P31513	UniProt accession no. P49326

Storage Class

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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