07-580

Anti-IKKε Antibody

Name: Anti-IKKε Antibody
Brand: MM

Upstate^®, from rabbit

Slide 1 of 1

Select a Size

Pricing and availability is not currently available.

About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

Key Documents

View All Documentation

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate^®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_014002

UniProt accession no.

Q14164

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... IKBKE(9641)
mouse ... Ikbke(56489)

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item	05-631	SAB3500452	ZRB2032
Sigma-Aldrich 07-580 Anti-IKKε Antibody	Sigma-Aldrich 05-631 Anti-IKKγ Antibody	Sigma-Aldrich SAB3500452 Anti-IKKε antibody produced in rabbit	Sigma-Aldrich ZRB2032 Anti-IKKε Antibody, clone 1D7 ZooMAb^® Rabbit Monoclonal
species reactivity human, mouse	species reactivity mouse, human	species reactivity human	species reactivity human, mouse
clone polyclonal	clone monoclonal	clone polyclonal	clone 1D7, recombinant monoclonal
biological source rabbit	biological source mouse	biological source rabbit	biological source rabbit
antibody form purified antibody	antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form purified antibody
technique(s) western blot: suitable	technique(s) western blot: suitable	technique(s) immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable	technique(s) immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable
shipped in wet ice	shipped in wet ice	shipped in dry ice	shipped in ambient

General description

Mr 80kDa

Immunogen

KLH-conjugated, synthetic peptide corresponding to amino acids 582-596 (SHLAKRLLQVFQEEC) of human IKKε

Application

Research Category
Signaling

Research Sub Category
Immunological Signaling

This Anti-IKKε Antibody is validated for use in WB for the detection of IKKε.

Biochem/physiol Actions

IKKε

Physical form

Format: Purified

Protein A purified

of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

Preparation Note

Stable for 2 years at -20°

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

IKKi/IKKepsilon plays a key role in integrating signals induced by pro-inflammatory stimuli.

Vladimir V Kravchenko et al.

The Journal of biological chemistry, 278(29), 26612-26619 (2003-05-09)

We report that the product of the inducible gene encoding the kinase known as IKKi/IKKepsilon (IKKi) is required for expression of a group of genes up-regulated by pro-inflammatory stimuli such as bacterial endotoxin (lipopolysaccharide (LPS)). Here, using murine embryonic fibroblasts

LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages.

Tina Ruggiero et al.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(9), 2898-2908 (2009-05-09)

The importance of post-transcriptional mechanisms for the regulation of the homoeostasis of the immune system and the response to challenge by microorganisms is becoming increasingly appreciated. We investigated the contribution of microRNAs (miRNAs) to macrophage activation induced by lipopolysaccharide (LPS).

Activation of NF-kappaB signaling by inhibitor of NF-kappaB kinase beta increases aggressiveness of ovarian cancer.

Lídia Hernandez et al.

Cancer research, 70(10), 4005-4014 (2010-04-29)

The NF-kappaB family of transcription factors has been implicated in the propagation of ovarian cancer, but the significance of constitutive NF-kappaB signaling in ovarian cancer is unknown. We hypothesized that constitutive NF-kappaB signaling defines a subset of ovarian cancer susceptible

Elevated expression of TANK-binding kinase 1 enhances tamoxifen resistance in breast cancer.

Congwen Wei et al.

Proceedings of the National Academy of Sciences of the United States of America, 111(5), E601-E610 (2014-01-23)

Resistance to antiestrogens is one of the major challenges in breast cancer treatment. Although phosphorylation of estrogen receptor α (ERα) is an important factor in endocrine resistance, the contributions of specific kinases in endocrine resistance are still not fully understood.

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service