M4880

Magnesium chloride

Name: Magnesium chloride
Brand: SIGMA

suitable for insect cell culture, BioReagent, ≥97.0%

Synonym(s):

Magnogene

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About This Item

Linear Formula:

MgCl₂

CAS Number:

7786-30-3

Molecular Weight:

95.21

NACRES:

NA.75

PubChem Substance ID:

24896955

UNSPSC Code:

12352302

EC Number:

232-094-6

MDL number:

MFCD00011106

Assay:

≥97.0%

Form:

powder

Solubility:

water: 468.7 g/L at 20 °C

Key Documents

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Product Name

Magnesium chloride, suitable for insect cell culture, BioReagent, ≥97.0%

InChI key

TWRXJAOTZQYOKJ-UHFFFAOYSA-L

InChI

1S/2ClH.Mg/h2*1H;/q;;+2/p-2

SMILES string

Cl[Mg]Cl

product line

BioReagent

assay

≥97.0%

form

powder

technique(s)

cell culture | insect: suitable

mp

714 °C (lit.)

solubility

water: 468.7 g/L at 20 °C

density

2.32 g/mL at 25 °C (lit.)

Quality Level

300

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Show Differences

1 of 4

This Item	449172	449164	208337
Sigma-Aldrich M4880 Magnesium chloride	Sigma-Aldrich 449172 Magnesium chloride	Sigma-Aldrich 449164 Magnesium chloride	Sigma-Aldrich 208337 Magnesium chloride
form powder	form -	form -	form powder
solubility water: 468.7 g/L at 20 °C	solubility -	solubility H₂O: slightly soluble(lit.)	solubility -
assay ≥97.0%	assay 99.99% trace metals basis	assay 99.9% trace metals basis	assay -
Quality Level 300	Quality Level 100	Quality Level 200	Quality Level 200
density 2.32 g/mL at 25 °C (lit.)	density 2.32 g/mL at 25 °C (lit.)	density 2.32 g/mL at 25 °C (lit.)	density 2.32 g/mL at 25 °C (lit.)
mp 714 °C (lit.)	mp 714 °C (lit.)	mp 714 °C (lit.)	mp 714 °C (lit.)

Application

Magnesium chloride has been used:

as a metal cofactor supplement in the terminal deoxynucleotidyl transferase (TdT) reaction[1]
as a component of Tris assay buffer to prepare substrate stocks for /-N-Acyl lysine substrate screening[2]
as a component of low-calcium differentiation medium for keratinocyte differentiation[3]

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number

0000520121

0000505297

0000507413

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Distribution and medical impact of loss-of-function variants in the Finnish founder population.

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Development of a robust and sensitive pyrosequencing assay for the detection of IDH1/2 mutations in gliomas.

Hideyuki Arita et al.

Brain tumor pathology, 32(1), 22-30 (2014-04-22)

Assessment of the mutational status of the isocitrate dehydrogenase 1/2 (IDH1/2) gene has become an integral part of the standard diagnostic procedure and, therefore, needs to be accurate. This may, however, be compromised by various factors including the method of

Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma.

Stephen Q Wong et al.

Oncotarget, 6(2), 1115-1127 (2014-12-30)

Melanoma is often caused by mutations due to exposure to ultraviolet radiation. This study reports a recurrent somatic C > T change causing a P131L mutation in the RQCD1 (Required for Cell Differentiation1 Homolog) gene identified through whole exome sequencing

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking.

Manal A Farg et al.

Human molecular genetics, 23(13), 3579-3595 (2014-02-20)

Intronic expansion of a hexanucleotide GGGGCC repeat in the chromosome 9 open reading frame 72 (C9ORF72) gene is the major cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. However, the cellular function of the C9ORF72 protein remains unknown.

PP2A delays APC/C-dependent degradation of separase-associated but not free securin.

Susanne Hellmuth et al.

The EMBO journal, 33(10), 1134-1147 (2014-05-02)

The universal triggering event of eukaryotic chromosome segregation is cleavage of centromeric cohesin by separase. Prior to anaphase, most separase is kept inactive by association with securin. Protein phosphatase 2A (PP2A) constitutes another binding partner of human separase, but the

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