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Merck

120650

Eshmuno® CMX Resin

Eshmuno® CMX

Synonym(s):

Eshmuno® CMX

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10 ML

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100 ML

RM 4,779.00

500 ML

RM 23,895.00

5000 ML

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About This Item

UNSPSC Code:
47101511

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ligand

(Carboxy and Alkyl Group)

Quality Level

sterility

sterile (Caustic Stable)

form

resin

specific analyte(s)

MAbs

parameter

300 cm/hr flow rate
8 bar max. pressure

matrix active group

polymer, polyvinyl ether

mean particle size

50 μm

capacity

60 mg binding capacity (pIgG/ml of resin)

application(s)

ADC
mAb

separation technique

mixed mode

storage temp.

2-30°C

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ligand

(Carboxy and Alkyl Group)

ligand

(Carboxyethyl with Alkyl-Functional Groups)

ligand

(Carboxyethyl with Alkyl-Functional Groups)

ligand

(Carboxyethyl with Alkyl-Functional Groups)

separation technique

mixed mode

separation technique

-

separation technique

-

separation technique

-

form

resin

form

prepacked column

form

prepacked column

form

prepacked column

matrix active group

polymer, polyvinyl ether

matrix active group

Polyvinyl Ether

matrix active group

Polyvinyl Ether

matrix active group

Polyvinyl Ether

specific analyte(s)

MAbs

specific analyte(s)

-

specific analyte(s)

-

specific analyte(s)

-

capacity

60 mg binding capacity (pIgG/ml of resin)

capacity

~60 mL, resin binding capacity

capacity

~60 mL, resin binding capacity

capacity

~60 mL, resin binding capacity

General description

Eshmuno® CMX chromatography resin is a mixed mode chromatography resin built on the proven Eshmuno® resin technology. This innovative resin combines weak cation exchange properties with hydrophobic interaction, providing high selectivity for Monoclonal Antibody (mAb), fusion protein and Antibody Drug Conjugate (ADCs) purification as well as separation of low molecular weight impurities, Host Cell Proteins (HCPs) and glycovariants.

Application

Purification of mAbs, ADCs, fusion proteins

Features and Benefits

Eshmuno® CMX chromatography resin enables users to
  • Intensify processes and decrease costs by reducing the number of chromatographic steps and buffer consumption
  • Improve performance with higher recovery rates, high selectivity and superior dynamic binding capacity
  • Improve the user experience with a broad operational window, simplified process development and easy column packing due to a rigid base bead

Legal Information

Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Flame

Signal Word

Warning

Hazard Statements

Hazard Classifications

Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

95.0 °F

Flash Point(C)

35 °C


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Articles

What antibody drug conjugates are, how bioconjugates work, design considerations and ADC services for ADC manufacturing, including bioconjugation.

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