C0985

Cytidine 3′,5′-cyclic monophosphate sodium salt

Name: Cytidine 3′,5′-cyclic monophosphate sodium salt
Brand: SIGMA
Price: 860 MYR

≥98% (HPLC)

Synonym(s):

cCMP sodium salt

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1 VIAL

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About This Item

Empirical Formula (Hill Notation):

C₉H₁₁N₃O₇PNa

CAS Number:

54925-33-6

Molecular Weight:

327.16

EC Number:

259-397-6

MDL number:

MFCD00037485

UNSPSC Code:

41106305

PubChem Substance ID:

329774833

NACRES:

NA.77

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description

1 vial contains 50μmol or approximately 16mg

Quality Level

200

Assay

≥98% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@@H]3COP([O-])(=O)O[C@H]3[C@H]2O

InChI

1S/C9H12N3O7P.Na/c10-5-1-2-12(9(14)11-5)8-6(13)7-4(18-8)3-17-20(15,16)19-7;/h1-2,4,6-8,13H,3H2,(H,15,16)(H2,10,11,14);/q;+1/p-1/t4-,6-,7-,8-;/m1./s1

InChI key

RZAHVNCNTLFRHJ-IAIGYFSYSA-M

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This Item	C9630	SML1228	D0260
Sigma-Aldrich C0985 Cytidine 3′,5′-cyclic monophosphate sodium salt	Sigma-Aldrich C9630 Cytidine 2′:3′-cyclic monophosphate monosodium salt	Sigma-Aldrich SML1228 Cyclic-di-GMP sodium salt	Sigma-Aldrich D0260 N⁶,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt
assay ≥98% (HPLC)	assay ≥95% (HPLC)	assay ≥98% (HPLC)	assay ≥97% (HPLC)
form powder	form powder	form powder	form powder
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 200
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
description 1 vial contains 50μmol or approximately 16mg	description -	description contains 1μmol of powder (approx. 0.7mg)	description -

Biochem/physiol Actions

Produced by the hydrolysis of cytidine 5′-triphosphate by the enzyme cytidylyl cyclase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Dibutyryl cyclic AMP induces differentiation of human neuroblastoma SH-SY5Y cells into a noradrenergic phenotype.

Toshiaki Kume et al.

Neuroscience letters, 443(3), 199-203 (2008-08-12)

Dibutyryl cyclic AMP (dbcAMP) and retinoic acid (RA) have been demonstrated to be the inducers of morphological differentiation in SH-SY5Y cells, a human catecholaminergic neuroblastoma cell line. However, it remains unclear whether morphologically differentiated SH-SY5Y cells by these compounds acquire

Identification of the Raf-1 signaling pathway used by cAMP to inhibit p42/p44 MAPK in rat lacrimal gland acini: role in potentiation of protein secretion.

Chika Funaki et al.

Investigative ophthalmology & visual science, 51(12), 6321-6328 (2010-07-31)

The lacrimal gland is primarily responsible for the aqueous portion of the tear film. Simultaneous addition of cholinergic agonists or growth factors with cAMP-dependent agonists potentiates secretion. Recent investigations revealed that cAMP decreases p44/p42 mitogen-activated protein kinase (MAPK) activity stimulated

Free tubulin modulates mitochondrial membrane potential in cancer cells.

Eduardo N Maldonado et al.

Cancer research, 70(24), 10192-10201 (2010-12-17)

Formation of the mitochondrial membrane potential (ΔΨ) depends on flux of respiratory substrates, ATP, ADP, and Pi through voltage-dependent anion channels (VDAC). As tubulin promotes single-channel closure of VDAC, we hypothesized that tubulin is a dynamic regulator of ΔΨ, which

Genistein decreases androgen biosynthesis in rat Leydig cells by interference with luteinizing hormone-dependent signaling.

Karen D Hancock et al.

Toxicology letters, 184(3), 169-175 (2008-12-09)

Testicular Leydig cells express estrogen receptors and are the predominant source of the male sex steroid hormone testosterone (T). Previous studies demonstrated that genistein acts through estrogen receptors in Leydig cells. In the present study, pre-treatment of Leydig cells isolated

Newton, R.P.

Nucleosides and Nucleotides, 14, 743-743 (1995)

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Cytidine 3′,5′-cyclic monophosphate sodium salt