APC
adenomatous polyposis coli
Synonimy:
BTPS2, DP2, DP2.5, DP3, GS, PPP1R46
Gatunek:
Human APC (324), Mouse Apc (11789), Rat Apc (24205), fruit fly Apc (44642), chicken APC (415607), Zebrafish apc (386762), dog APC (479139), domestic cat APC (101096138), Horse APC (100064431), cow APC (533233) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(324) Summary: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
- Mouse(11789) adenomatosis polyposis coli
- Rat(24205) adenomatous polyposis coli
- fruit fly(44642) APC-like
- chicken(415607) adenomatous polyposis coli
- Zebrafish(386762) adenomatosis polyposis coli
- dog(479139) adenomatous polyposis coli
- domestic cat(101096138) adenomatous polyposis coli
- Horse(100064431) adenomatous polyposis coli
- cow(533233) adenomatous polyposis coli
- sheep(101104664) adenomatous polyposis coli
- domestic guinea pig(100723694) adenomatous polyposis coli
- naked mole-rat(101704055) adenomatous polyposis coli
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-APCS antibody produced in mouse, clone 4E8, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
Przeciwciało anty-APC, CT, klon przeciwciała C-APC 28.9, bez wodobrzusza, clone C-APC 28.9, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Przeciwciało przeciw surowiczemu amyloidowi P, klon 5.4D.3B, clone 5.4D.3B, Chemicon®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
Anti-APC Antibody, clone CC-1, clone CC-1, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-APC Antibody, clone FE9, clone FE9, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Cell Lines
Numer produktu
Opis
Gatunek