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Merck

ATP1A2

ATPase, Na+/K+ transporting, alpha 2 polypeptide

Synonimy:
FHM2, MHP2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(477) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008]
  • Mouse(98660) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • Rat(24212) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • Horse(100058251) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • chicken(396468) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • dog(488636) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • domestic guinea pig(100729524) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • naked mole-rat(101721770) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • cow(515161) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • sheep(101118148) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • Domestic Rabbit(100008756) ATPase, Na+/K+ transporting, alpha 2 polypeptide
  • domestic cat(101096785) ATPase, Na+/K+ transporting, alpha 2 polypeptide

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anty-ATP1A2, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Przeciwciało anty-Na+K+ ATPaza α-2, serum, Upstate®,
Reaktywność gatunkowa
rat
Zastosowanie
western blot
Anti-Sodium Pump Subunit alpha-2 Antibody, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
bovine, human, mouse, porcine, rat
Zastosowanie
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Digoxin, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Digoxin, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Digoxin, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Digoxin, analytical standard,
Gatunek
human
Digitoxin for LC assay, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human ATP1A2,
Gatunek
human